Volume 55, Issue 3, Pages (March 1999)

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Volume 55, Issue 3, Pages 984-994 (March 1999) Glomerular size-selective dysfunction in NIDDM is not ameliorated by ACE inhibition or by calcium channel blockade  Piero Ruggenenti, Lidia Mosconi, Fabio Sangalli, Federica Casiraghi, Vincenzo Gambara, Giuseppe Remuzzi, Andrea Remuzzi  Kidney International  Volume 55, Issue 3, Pages 984-994 (March 1999) DOI: 10.1046/j.1523-1755.1999.055003984.x Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 1 Schematic representation of the study protocol. A description of the study design is in the text. Symbols are: (□) 24-hour protein excretion; (▩) clearance study. Kidney International 1999 55, 984-994DOI: (10.1046/j.1523-1755.1999.055003984.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 2 Fractional clearance of neutral dextrans in normal controls and in diabetic patients at baseline evaluation. Symbols are: (•) NIDDM baseline; (□) healthy controls; *P < 0.05 vs. healthy controls; **P < 0.01 vs. healthy controls. Kidney International 1999 55, 984-994DOI: (10.1046/j.1523-1755.1999.055003984.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 3 Fractional clearance of neutral dextrans in diabetic patients at the end of the treatment period with perindopril (A) and nitrendipine (B). Symbols are: (•) NIDDM baseline; (◊) NIDDM + perindopril; (○) NIDDM + nitrendipine. Kidney International 1999 55, 984-994DOI: (10.1046/j.1523-1755.1999.055003984.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 4 Fraction of filtrate as a function of pore radii [r4g (r)] in healthy controls and in diabetic patients at baseline evaluation and at the end of perindopril and nitrendipine treatment. Kidney International 1999 55, 984-994DOI: (10.1046/j.1523-1755.1999.055003984.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Kidney International 1999 55, 984-994DOI: (10. 1046/j. 1523-1755. 1999 Kidney International 1999 55, 984-994DOI: (10.1046/j.1523-1755.1999.055003984.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Kidney International 1999 55, 984-994DOI: (10. 1046/j. 1523-1755. 1999 Kidney International 1999 55, 984-994DOI: (10.1046/j.1523-1755.1999.055003984.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Kidney International 1999 55, 984-994DOI: (10. 1046/j. 1523-1755. 1999 Kidney International 1999 55, 984-994DOI: (10.1046/j.1523-1755.1999.055003984.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Kidney International 1999 55, 984-994DOI: (10. 1046/j. 1523-1755. 1999 Kidney International 1999 55, 984-994DOI: (10.1046/j.1523-1755.1999.055003984.x) Copyright © 1999 International Society of Nephrology Terms and Conditions