HeartRhythm Case Reports

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Date of download: 6/28/2016 Copyright © The American College of Cardiology. All rights reserved. From: Significance of Non-Type 1 Anterior Early Repolarization.
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Abnormal epicardial electrophysiologic substrate in patients with early repolarization pattern and reduced left ventricular systolic function: A report.
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HeartRhythm Case Reports
Presentation transcript:

HeartRhythm Case Reports Reproducibility and diagnostic usefulness of repeated sodium channel blocker test at higher precordial electrocardiogram recording in a patient with Brugada syndrome  Eiichiro Nakagawa, MD, PhD, Takahiko Naruko, MD, PhD, Toshinori Makita, MD, PhD  HeartRhythm Case Reports  DOI: 10.1016/j.hrcr.2019.01.010 Copyright © 2019 Heart Rhythm Society Terms and Conditions

Figure 1 A: A 12-lead electrocardiogram (ECG) recorded 1 hour after ventricular fibrillation showing a slight QRS prolongation with a QRS duration of 125 ms and up-sloping ST depression in precordial leads. B: A 12-lead ECG recorded 10 hours after ventricular fibrillation showing early repolarization in the inferior and lateral leads with a narrower QRS duration of 110 ms. HeartRhythm Case Reports DOI: (10.1016/j.hrcr.2019.01.010) Copyright © 2019 Heart Rhythm Society Terms and Conditions

Figure 2 Drug challenge test performed with intravenous 50 mg pilsicainide on the fourth admission day. Early repolarization pattern was present in the inferior leads before drug administration and saddleback-type ST-segment elevation with a J-point amplitude of 0.3 mV was provoked in lead V2 at the third intercostal space after drug administration. 3ICS = electrocardiogram was recorded at third intercostal space in leads V1, V2, and V3; 4ICS = electrocardiogram at fourth intercostal space. HeartRhythm Case Reports DOI: (10.1016/j.hrcr.2019.01.010) Copyright © 2019 Heart Rhythm Society Terms and Conditions

Figure 3 Repeat drug challenge test with intravenous 50 mg pilsicainide was performed on the 24th admission day. Saddleback-type ST-segment elevation was observed in lead V2 at the third intercostal space, with a J-point amplitude of 0.35 mV before drug administration, and coved-type ST-segment elevation was induced in leads V1 and V2 with a J-point amplitude of 0.22 and 0.52 mV, respectively, at the third intercostal space after drug administration. 3ICS = electrocardiogram was recorded at third intercostal space in leads V1, V2, and V3; 4ICS = electrocardiogram at fourth intercostal space. HeartRhythm Case Reports DOI: (10.1016/j.hrcr.2019.01.010) Copyright © 2019 Heart Rhythm Society Terms and Conditions

Supplemental Figure 1 Spontaneous coved-type ST-segment elevation was observed in leads V1 and V2 both at the usual fourth and third intercostal spaces 1 year after ventricular fibrillation. 3ICS = ECG was recorded at third intercostal space in leads V1, V2, and V3; 4ICS = ECG was recorded at fourth intercostal space. HeartRhythm Case Reports DOI: (10.1016/j.hrcr.2019.01.010) Copyright © 2019 Heart Rhythm Society Terms and Conditions