Prenatal exposure to bisphenol A and phthalates and childhood respiratory tract infections and allergy Mireia Gascon, MSc, Maribel Casas, PhD, Eva Morales,

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Presentation transcript:

Prenatal exposure to bisphenol A and phthalates and childhood respiratory tract infections and allergy Mireia Gascon, MSc, Maribel Casas, PhD, Eva Morales, PhD, Damaskini Valvi, MSc, Ana Ballesteros-Gómez, PhD, Noelia Luque, PhD, Soledad Rubio, PhD, Núria Monfort, PhD, Rosa Ventura, PharmD, David Martínez, BSc, Jordi Sunyer, PhD, Martine Vrijheid, PhD Journal of Allergy and Clinical Immunology Volume 135, Issue 2, Pages 370-378.e7 (February 2015) DOI: 10.1016/j.jaci.2014.09.030 Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Adjusted associations between maternal urinary BPA and phthalate metabolite concentrations (RR per doubling concentration [levels were log2 transformed]) and occurrence of wheeze (A), chest infections (B), and bronchitis (C) at each age at follow-up from birth until age 7 years. BPA models were adjusted for maternal education, number of siblings and maternal smoking during pregnancy, and phthalate models were adjusted additionally for maternal history of asthma/allergy and maternal body mass index. The Σ4DEHP metabolites include MEHHP, MEHP, MEOHP, and MECPP. The Σ3LMWP metabolites include MEP, MiBP, and MnBP. Journal of Allergy and Clinical Immunology 2015 135, 370-378.e7DOI: (10.1016/j.jaci.2014.09.030) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E1 DAG for BPA. Journal of Allergy and Clinical Immunology 2015 135, 370-378.e7DOI: (10.1016/j.jaci.2014.09.030) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E2 DAG for phthalates. Journal of Allergy and Clinical Immunology 2015 135, 370-378.e7DOI: (10.1016/j.jaci.2014.09.030) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions