(A) Percentage of emphysematous lung (Emph%), (B) functional small airway disease (fSAD%), (C) tissue fraction at inspiration (βtissue), (D) fractional.

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(A) Percentage of emphysematous lung (Emph%), (B) functional small airway disease (fSAD%), (C) tissue fraction at inspiration (βtissue), (D) fractional lobar air-volume change (ΔV air f), (E) the determinant of Jacobian (Jacobian) and (F) anisotropic deform... (A) Percentage of emphysematous lung (Emph%), (B) functional small airway disease (fSAD%), (C) tissue fraction at inspiration (βtissue), (D) fractional lobar air-volume change (ΔVairf), (E) the determinant of Jacobian (Jacobian) and (F) anisotropic deformation index (ADI) among healthy, asthmatic and chronic obstructive pulmonary disease (COPD) subjects. Values are presented as mean (±CI). *P<0.01 for healthy versus asthmatic subjects. †P<0.01 with red-dashed box for asthmatic versus COPD subjects. ‡P<0.01 for COPD subjects versus healthy subjects. LLL, left lower lobe; LUL, left upper lobe; RLL, right lower lobe; RML, right middle lobe; RUL, right upper lobe. Sanghun Choi et al. BMJ Open Resp Res 2017;4:e000252 ©2017 by British Thoracic Society