A Method that Will Captivate U

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A Method that Will Captivate U Sophie Martin, Jeff Coller Molecular Cell Volume 59, Issue 5, Pages 716-717 (September 2015) DOI: 10.1016/j.molcel.2015.08.017 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Chemical Structures of 4-Thiouridine and Uridine Nucleosides The nucleoside 4-thiouridine (left) can be incorporated into RNA strands instead of uridine (right). The thiol group can then react with disulfide chemistries to lead to biotinylated s4U-RNA, allowing the specific purification of labeled RNA from the cell. Molecular Cell 2015 59, 716-717DOI: (10.1016/j.molcel.2015.08.017) Copyright © 2015 Elsevier Inc. Terms and Conditions