European Society of Clinical Microbiology and Infectious Diseases: update of the diagnostic guidance document for Clostridium difficile infection M.J.T.

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European Society of Clinical Microbiology and Infectious Diseases: update of the diagnostic guidance document for Clostridium difficile infection M.J.T. Crobach, T. Planche, C. Eckert, F. Barbut, E.M. Terveer, O.M. Dekkers, M.H. Wilcox, E.J. Kuijper Clinical Microbiology and Infection Volume 22, Pages S63-S81 (August 2016) DOI: 10.1016/j.cmi.2016.03.010 Copyright © 2016 The Authors Terms and Conditions

Fig. 1 Summary of selection process. *Some studies had more than one reason for exclusion. Clinical Microbiology and Infection 2016 22, S63-S81DOI: (10.1016/j.cmi.2016.03.010) Copyright © 2016 The Authors Terms and Conditions

Fig. 2 Quality assessment of included studies. Clinical Microbiology and Infection 2016 22, S63-S81DOI: (10.1016/j.cmi.2016.03.010) Copyright © 2016 The Authors Terms and Conditions

Fig. 3 Recommended algorithms for CDI testing. (a) GDH or NAAT–Tox A/B algorithm. (b) GDH and Tox A/B–NAAT/TC algorithm. CDI, Clostridium difficile infection; GDH, glutamate dehydrogenase; NAAT, nucleic acid amplification test; TC, toxigenic culture; Tox A/B, toxin A/B; EIA, enzyme immunoassay. Clinical Microbiology and Infection 2016 22, S63-S81DOI: (10.1016/j.cmi.2016.03.010) Copyright © 2016 The Authors Terms and Conditions