Volume 60, Issue 2, Pages (August 2001)

Slides:

Advertisements

Similar presentations

Figure 5. 1,25-(OH)2D plus Dex dose response for increased mMCSF by RT-PCR. Semiquantitative RT-PCR for mMCSF and GAP was performed in controls.

Advertisements

Volume 63, Issue 2, Pages (February 2003)

Volume 59, Issue 4, Pages (April 2001)

The roles of IGF-I and IGFBP-3 in the regulation of proximal tubule, and renal cell carcinoma cell proliferation Catherine W. Cheung, David A. Vesey,

Toshiaki Monkawa, Tadashi Yoshida, Matsuhiko Hayashi, Takao Saruta

Volume 59, Issue 3, Pages (March 2001)

Volume 54, Issue 5, Pages (November 1998)

Requirement of heat shock protein 90 in mesangial cell mitogenesis

From secondary to primary prevention of progressive renal disease: The case for screening for albuminuria Paul E. De Jong, Barry M. Brenner Kidney International

Volume 63, Issue 6, Pages (June 2003)

c-myc antisense oligonucleotide treatment ameliorates murine ARPKD

Volume 61, Issue 5, Pages (May 2002)

Volume 67, Issue 4, Pages (April 2005)

Vitamin E attenuates crystal formation in rat kidneys: Roles of renal tubular cell death and crystallization inhibitors H.-S. Huang, J. Chen, C.-F. Chen,

Screening for genes up-regulated in 5/6 nephrectomized mouse kidney

Volume 61, Issue 6, Pages (June 2002)

Volume 58, Issue 2, Pages (August 2000)

Shiga toxin 1 elicits diverse biologic responses in mesangial cells

Volume 61, Issue 5, Pages (May 2002)

Expression of inter-α-trypsin inhibitor and tumor necrosis factor-stimulated gene 6 in renal proximal tubular epithelial cells Ulf Janssen, Gareth Thomas,

Volume 65, Issue 6, Pages (June 2004)

Karl A. Nath, Anthony J. Croatt, Jill J. Haggard, Joseph P. Grande

Volume 56, Issue 2, Pages (August 1999)

Volume 60, Issue 5, Pages (November 2001)

PPARα agonist fenofibrate improves diabetic nephropathy in db/db mice

Volume 67, Issue 5, Pages (May 2005)

Gene transfer of truncated IκBα prevents tubulointerstitial injury

The roles of IGF-I and IGFBP-3 in the regulation of proximal tubule, and renal cell carcinoma cell proliferation Catherine W. Cheung, David A. Vesey,

Volume 69, Issue 2, Pages (January 2006)

Wei-Zhong Ying, Paul W. Sanders Kidney International

Epiphyseal growth plate growth hormone receptor signaling is decreased in chronic kidney disease–related growth retardation Ariel Troib, Daniel Landau,

Volume 57, Issue 3, Pages (March 2000)

Aquaporin gene delivery to kidney

Volume 79, Issue 4, Pages (February 2011)

Volume 57, Issue 5, Pages (May 2000)

Volume 58, Issue 4, Pages (October 2000)

Izabella Z.A. Pawluczyk, Kevin P.G. Harris Kidney International

Glomerular injury is exacerbated in diabetic integrin α1-null mice

Glucocorticoids enhance the expression of the basolateral Na+:HCO3- cotransporter in renal proximal tubules Raza Ali, Hassane Amlal, Charles E. Burnham,

Volume 72, Issue 5, Pages (September 2007)

Volume 56, Issue 3, Pages (September 1999)

Transient neonatal cystinuria

Volume 68, Issue 2, Pages (August 2005)

Volume 63, Issue 1, Pages (January 2003)

Volume 58, Issue 2, Pages (August 2000)

Volume 59, Issue 1, Pages (January 2001)

Volume 67, Issue 6, Pages (June 2005)

Chien-Te Lee, Viet M. Huynh, Li-Wen Lai, Yeong-Hau H. Lien

Volume 54, Issue 1, Pages (July 1998)

Harold M. Aukema, Ihsan Housini Kidney International

Volume 64, Issue 3, Pages (September 2003)

Yasunori Kitamoto, Katsuhiko Matsuo, Kimio Tomita Kidney International

Volume 67, Issue 6, Pages (June 2005)

It's not over till the last glomerulus forms

Endothelin antagonists in renal disease

Nosratola D. Vaziri, M.D., Kaihui Liang Kidney International

Volume 59, Issue 2, Pages (February 2001)

Volume 80, Issue 10, Pages (November 2011)

Volume 68, Pages S98-S102 (December 2005)

Volume 70, Issue 3, Pages (August 2006)

Volume 58, Issue 6, Pages (December 2000)

Volume 74, Issue 8, Pages (October 2008)

c-myc antisense oligonucleotide treatment ameliorates murine ARPKD

T-PA promotes glomerular plasmin generation and matrix degradation in experimental glomerulonephritis Masashi Haraguchi, Wayne A. Border, Yufeng Huang,

Estrogen downregulates the proximal tubule type IIa sodium phosphate cotransporter causing phosphate wasting and hypophosphatemia S. Faroqui, M. Levi,

Volume 65, Issue 6, Pages (June 2004)

Volume 59, Issue 2, Pages (February 2001)

Volume 65, Issue 6, Pages (June 2004)

The Ebf1 knockout mouse and glomerular maturation

Volume 56, Issue 6, Pages (December 1999)

Presentation transcript:

Volume 60, Issue 2, Pages 505-512 (August 2001) A novel somatostatin analogue prevents early renal complications in the nonobese diabetic mouse Daniel Landau, Yael Segev, Michel Afargan, Aviva Silbergeld, Leonid Katchko, Andrey Podshyvalov, Moshe Phillip Kidney International Volume 60, Issue 2, Pages 505-512 (August 2001) DOI: 10.1046/j.1523-1755.2001.060002505.x Copyright © 2001 International Society of Nephrology Terms and Conditions

Figure 1 Mean serum growth hormone (GH; ng/mL) (A) and insulin-like growth factor-I (IGF-I; ng/mL) (B) levels on day 21 in the control (C), PTR-3173–treated C (CS), untreated diabetic (D), and PTR-3173–treated diabetic (DS) groups. Values are mean ± SEM; N = 6 in each group. *P < 0.05 vs. C. Kidney International 2001 60, 505-512DOI: (10.1046/j.1523-1755.2001.060002505.x) Copyright © 2001 International Society of Nephrology Terms and Conditions

Figure 2 Mean absolute kidney weight (mg) (A), glomerular volume (105 μm3) (B) and kidney-extractable IGF-I protein (ng/g tissue) (C) on day 21 in the control untreated (C), PTR-3173–treated C (CS), untreated diabetic (D) and PTR-3173–treated diabetic (DS) groups. Values are mean ± SEM; N = 6 in each group. *P < 0.05 vs. C. Kidney International 2001 60, 505-512DOI: (10.1046/j.1523-1755.2001.060002505.x) Copyright © 2001 International Society of Nephrology Terms and Conditions

Figure 3 (A) Northern blot analysis of kidney IGFBP-1 mRNA, using 40 μg total RNA, on day 21 in the control (C), PTR-3173–treated C (CS), untreated diabetic (D), and PTR-3173–treated diabetic (DS) groups. The 1.6kb bands corresponding to the IGFBP-1 transcript are shown in the upper lane. The film was exposed for 48 hours at -70°C with two intensifying screens. The ethidium bromide staining of the 18S and 28S ribosomal RNA of the samples prior to their transfer to the membrane appears in the lower lane. (B) Quantitation of kidney IGFBP-1 mRNA levels from the autoradiograph shown in Figure 4a, using a phosphorimager. The data are expressed as the percentage of control. *P < 0.05 vs. C and DS. Kidney International 2001 60, 505-512DOI: (10.1046/j.1523-1755.2001.060002505.x) Copyright © 2001 International Society of Nephrology Terms and Conditions

Figure 4 Urinary albumin excretion (μg/24 h) (A) and creatinine clearance (μL/min) (B) on day 21 in the control untreated (C), PTR-3173–treated C (CS), untreated diabetic (D), and PTR-3173–treated diabetic (DS) groups. Values are mean ± SEM; N = 7 to 10 in each group. *P < 0.05 vs. C; †P < 0.05 vs. D. Kidney International 2001 60, 505-512DOI: (10.1046/j.1523-1755.2001.060002505.x) Copyright © 2001 International Society of Nephrology Terms and Conditions