Blood glucose concentration profile after 10 mg dexamethasone in non-diabetic and type 2 diabetic patients undergoing abdominal surgery Hans P , Vanthuyne.

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Blood glucose concentration profile after 10 mg dexamethasone in non-diabetic and type 2 diabetic patients undergoing abdominal surgery Hans P , Vanthuyne A , Dewandre P.Y. , Brichant J.F. , Bonhomme V British Journal of Anaesthesia Volume 97, Issue 2, Pages 164-170 (August 2006) DOI: 10.1093/bja/ael111 Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

Fig 1 Blood glucose concentration [mean (sd)] profile in non-diabetic (ND, open squares) and type 2 diabetic (D, closed squares) patients from induction of anaesthesia (T0) to 60, 120, 180 and 240 min (T1, T2, T3 and T4) after dexamethasone administration. *Blood glucose concentration significantly higher in Group D than in Group ND throughout the study period and significantly higher at T2 than at all other time points in both groups. British Journal of Anaesthesia 2006 97, 164-170DOI: (10.1093/bja/ael111) Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

Fig 2 Blood glucose concentration expressed as % of baseline [mean (sd)] in non-diabetic (ND, open squares) and type 2 diabetic (D, closed squares) patients from T1 to T4. The way of calculating % of baseline can be found in the text. *Blood glucose concentration in % of baseline significantly higher at T2 than at T1, T3 and T4 in both groups. +Blood glucose concentration significantly higher at T3 than at T4 in both groups. British Journal of Anaesthesia 2006 97, 164-170DOI: (10.1093/bja/ael111) Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

Fig 3 Least square linear regression between maximum blood glucose concentration observed during the study period and BMI (a) or HbA (1c) (b). The equation of the regression line is given, and the squared correlation coefficient. British Journal of Anaesthesia 2006 97, 164-170DOI: (10.1093/bja/ael111) Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

Fig 4 Binary logistic regression between BMI (kg m−2) and HbA (1c) (%) on one hand, and the probability of observing a blood glucose level higher than 8.33 mmol litre−1 during 240 min after dexamethasone administration, on the other hand. The equation provided by the analysis is logit(P)=0.137 BMI+0.936 HbA (1c)−10.538, where logit(P)=ln [P/(1−P)] and P=probability of observing a blood glucose concentration higher than 8.33 mmol litre−1. Nagelkerke pseudo R2=0.306, Hosmer and Lemeshow χ ( 8 ) 2 = 7.485 , P=0.485. The isocurve of the 50% probability of observing a blood glucose level higher than 8.33 mmol litre−1 is shown by the thick straight line. Circles correspond to individual recordings of BMI and HbA (1c) in non-diabetic (open) and type 2 diabetic (closed) patients plotted against the probability calculated according to the logistic regression model. British Journal of Anaesthesia 2006 97, 164-170DOI: (10.1093/bja/ael111) Copyright © 2006 British Journal of Anaesthesia Terms and Conditions