Ecological effects on the oro- and nasopharyngeal microflora in children after treatment of acute otitis media with cefuroxime axetil or amoxycillin-clavulanate.

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Presentation transcript:

Ecological effects on the oro- and nasopharyngeal microflora in children after treatment of acute otitis media with cefuroxime axetil or amoxycillin-clavulanate as suspensions B. Lund, C. Edlund, B. Rynnel-Dagöö, Y. Lundgren, J. Sterner, C.E. Nord Clinical Microbiology and Infection Volume 7, Issue 5, Pages 230-237 (May 2001) DOI: 10.1046/j.1469-0691.2001.00242.x Copyright © 2001 European Society of Clinical Infectious Diseases Terms and Conditions

Figure 1 Impact of treatment with amoxycillin-clavulanate (13.3 mg/kg three times daily) on the aerobic oropharyngeal microflora (n = 12). Each symbol (•) represents data from one subject. Dotted line illustrates the median value for the 12 subjects at different time points. Clinical Microbiology and Infection 2001 7, 230-237DOI: (10.1046/j.1469-0691.2001.00242.x) Copyright © 2001 European Society of Clinical Infectious Diseases Terms and Conditions

Figure 2 Impact of treatment with cefuroxime axetil (15.5 mg/kg twice daily) on the aerobic oropharyngeal microflora (n = 1). Each symbol (•) represents data from one subject. Dotted line illustrates the median value for the seven subjects at different time points. Clinical Microbiology and Infection 2001 7, 230-237DOI: (10.1046/j.1469-0691.2001.00242.x) Copyright © 2001 European Society of Clinical Infectious Diseases Terms and Conditions

Figure 3 Impact of treatment with amoxycillin-clavulanate or cefuroxime axetil on the anaerobic oropharyngeal microflora. Each symbol (•) represents data from one subject. Dotted line illustrates the median value at different time points. Clinical Microbiology and Infection 2001 7, 230-237DOI: (10.1046/j.1469-0691.2001.00242.x) Copyright © 2001 European Society of Clinical Infectious Diseases Terms and Conditions

Figure 4 Impact of amoxycillin-clavulanate (n = 12) or cefuroxime axetil (n = 7) on the colonization of pathogens in nasopharynx. Moraxella catarrhalis; ▪ Haemophilus influenzae; □ Streptococcus pneumoniae; Various other pathogens. Clinical Microbiology and Infection 2001 7, 230-237DOI: (10.1046/j.1469-0691.2001.00242.x) Copyright © 2001 European Society of Clinical Infectious Diseases Terms and Conditions