The risk and extent of neurologic events are equivalent for high-risk patients treated with transcatheter or surgical aortic valve replacement Thomas.

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Presentation transcript:

The risk and extent of neurologic events are equivalent for high-risk patients treated with transcatheter or surgical aortic valve replacement Thomas G. Gleason, MD, John T. Schindler, MD, David H. Adams, MD, Michael J. Reardon, MD, Neal S. Kleiman, MD, Louis R. Caplan, MD, John V. Conte, MD, G. Michael Deeb, MD, G. Chad Hughes, MD, Sharla Chenoweth, MS, Jeffrey J. Popma, MD The Journal of Thoracic and Cardiovascular Surgery Volume 152, Issue 1, Pages 85-96 (July 2016) DOI: 10.1016/j.jtcvs.2016.02.073 Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Patient disposition. TAVR, Transcatheter aortic valve replacement; SAVR, surgical aortic valve replacement. The Journal of Thoracic and Cardiovascular Surgery 2016 152, 85-96DOI: (10.1016/j.jtcvs.2016.02.073) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Kaplan-Meier analysis for (A) stroke or TIA and (B) major stroke in the TAVR and SAVR arms of the High-Risk Pivotal Trial through 2 years. TAVR, Transcatheter aortic valve replacement; SAVR, surgical aortic valve replacement; TIA, transient ischemic attack. The Journal of Thoracic and Cardiovascular Surgery 2016 152, 85-96DOI: (10.1016/j.jtcvs.2016.02.073) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Distribution of the occurrences of TIAs and major and minor strokes through (A) 30 days and (B) 2 years. TAVR, Transcatheter aortic valve replacement; SAVR, surgical aortic valve replacement; TIA, transient ischemic attack. The Journal of Thoracic and Cardiovascular Surgery 2016 152, 85-96DOI: (10.1016/j.jtcvs.2016.02.073) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 4 Kaplan-Meier estimates of mortality for (A) patients with any stroke and (B) patients with major stroke within 30 days for the TAVR and SAVR arms of the High- Risk Pivotal Trial through 2 years. This time-to-event analysis assigned the day on which the stroke event occurred as day 0. TAVR, Transcatheter aortic valve replacement; SAVR, surgical aortic valve replacement. The Journal of Thoracic and Cardiovascular Surgery 2016 152, 85-96DOI: (10.1016/j.jtcvs.2016.02.073) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Kaplan-Meier analysis for major stroke after TAVR or SAVR. The Journal of Thoracic and Cardiovascular Surgery 2016 152, 85-96DOI: (10.1016/j.jtcvs.2016.02.073) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

The Journal of Thoracic and Cardiovascular Surgery 2016 152, 85-96DOI: (10.1016/j.jtcvs.2016.02.073) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions