A. Vasudevan, C.E. Snowman, S. Sundar, T.W. Sarge, P.E. Hess

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Presentation transcript:

Intrathecal morphine reduces breakthrough pain during labour epidural analgesia A. Vasudevan, C.E. Snowman, S. Sundar, T.W. Sarge, P.E. Hess British Journal of Anaesthesia Volume 98, Issue 2, Pages 241-245 (February 2007) DOI: 10.1093/bja/ael346 Copyright © 2007 British Journal of Anaesthesia Terms and Conditions

Fig 1 Number of episodes of breakthrough pain during epidural analgesia. The MS group received 100 µg morphine and the PLCB group received an equal volume of saline. Episode of breakthrough pain was defined as pain or pressure that was successfully treated by supplemental medications. Breakthrough pain was treated by protocol. The morphine group had significantly fewer episodes than the placebo group [0.6 (0.6) vs 1.1 (0.8), P = 0.008]. British Journal of Anaesthesia 2007 98, 241-245DOI: (10.1093/bja/ael346) Copyright © 2007 British Journal of Anaesthesia Terms and Conditions

Fig 2 Pain-free survival. This figure shows the Kaplan–Meier survival curve for the cumulative duration of pain-free analgesia in the MS group vs the PLCB group. The MS group had a significantly longer pain-free period (300 min) than did the PLCB group (180 min); P = 0.03 by log-rank analysis. Crosses represent subjects who delivered without requesting supplementation. British Journal of Anaesthesia 2007 98, 241-245DOI: (10.1093/bja/ael346) Copyright © 2007 British Journal of Anaesthesia Terms and Conditions