Volume 119, Issue 6, Pages 1631-1636 (December 2000) Epidemiology and natural history of primary biliary cirrhosis in a U.S. community  W.Ray Kim, *,‡, Keith D. Lindor, *, G.Richard Locke, Terry M. Therneau, ‡, Henry A. Homburger, §, Kenneth P. Batts, §, Barbara P. Yawn, ∥, Janice L. Petz, *, L.Joseph Melton, E.Rolland Dickson, *  Gastroenterology  Volume 119, Issue 6, Pages 1631-1636 (December 2000) DOI: 10.1053/gast.2000.20197 Copyright © 2000 American Gastroenterological Association Terms and Conditions

Fig. 1 Age- and sex-specific incidence of PBC adjusted by age and gender to the population distribution of U.S. whites in 1990. As expected, PBC was most common in women between 40 and 80 years of age. Gastroenterology 2000 119, 1631-1636DOI: (10.1053/gast.2000.20197) Copyright © 2000 American Gastroenterological Association Terms and Conditions

Fig. 2 (A) Survival of patients with PBC (n = 46) compared with the age- and sex-matched Minnesota white population. Time 0 corresponds to the earliest time that the diagnosis of PBC could be established. Patients with PBC have significantly shorter survival than the population control (P < 0.01). (B) Survival of patients with PBC compared with the estimation made by the Mayo natural history model. Time 0 represents the earliest time complete data were available to apply the Mayo model (n = 41). The Mayo model accurately reflected actual patient survival (P = 0.69). Gastroenterology 2000 119, 1631-1636DOI: (10.1053/gast.2000.20197) Copyright © 2000 American Gastroenterological Association Terms and Conditions