Volume 386, Issue 9998, Pages (September 2015)

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Volume 386, Issue 9998, Pages 1066-1073 (September 2015) Bronchoscopic lung volume reduction with endobronchial valves for patients with heterogeneous emphysema and intact interlobar fissures (the BeLieVeR-HIFi study): a randomised controlled trial Claire Davey, MSc, Zaid Zoumot, PhD, Simon Jordan, MD, William H McNulty, MBBS, Dennis H Carr, MD, Matthew D Hind, PhD, Prof David M Hansell, MD, Michael B Rubens, MBBS, Winston Banya, MSc, Prof Michael I Polkey, PhD, Pallav L Shah, MD, Dr Nicholas S Hopkinson, PhD The Lancet Volume 386, Issue 9998, Pages 1066-1073 (September 2015) DOI: 10.1016/S0140-6736(15)60001-0 Copyright © 2015 Davey et al. Open Access article distributed under the terms of CC BY Terms and Conditions

Figure 1 Trial profile 6MWD=6 min walking distance. PFTs=pulmonary function tests. COPD=chronic obstructive pulmonary disease. The Lancet 2015 386, 1066-1073DOI: (10.1016/S0140-6736(15)60001-0) Copyright © 2015 Davey et al. Open Access article distributed under the terms of CC BY Terms and Conditions

Figure 2 Change in forced expiratory volume in 1 s (FEV1) at 3 months in patients treated with bronchoscopic lung volume reduction with endobronchial valves compared with controls who underwent sham treatment Bars are mean and 95% CIs. Red symbols represent the four patients who had collateral ventilation detected using the Chartis system and were treated with bronchoscopic lung volume reduction. The Lancet 2015 386, 1066-1073DOI: (10.1016/S0140-6736(15)60001-0) Copyright © 2015 Davey et al. Open Access article distributed under the terms of CC BY Terms and Conditions