The Science of “PMSing”

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Presentation transcript:

The Science of “PMSing” Progesterone & Estrogen Chandana & Pranita

About Progesterone Secreted by the corpus luteum Steroid Target tissue- the uterus Maintains the uterine lining built by estrogen Prepares mammary glands for secretory functions Prepares and maintains uterus for embryo if egg is fertilized In the event that the egg is fertilized, it signals the lining to stimulate the growth of blood vessels to nourish the embryo

Controlling Progesterone

Progesterone’s Role in Homeostasis Progesterone has bone forming activity Binds to receptors on osteoblasts to signal bone forming activity Maintains lining Regulates pregnancy

Consequences of hyper and hypo secretion Too little: - If pregnant, can lead to miscarriage -Irregular and heavy menustrations -anxiety -PMS Too much: - fatigue -dizziness -water retention -depression

Estrogen Estrone,Estradiol,Estriol Steroid Hormone Multiple target tissues (Bones,Liver) Estrogen is required to form the ovum during oogenesis Prepares uterus for ovum Released by the ovaries,placenta,corpus luteum

Maintaining Homeostasis Energy Expenditure Adipose tissue distribution Food intake Regulates body development Menstrual Cycle in women

Consequences of Hypo & Hyper Secretion worsen pre-existing ovarian or breast cancers Ovulation decreases or stops all together Hypo - Obesity Mood Swings affects absorption and utilization of calcium and vitamin D (Osteoporosis) Fetal Demise (in Pregnant women) Congenital Adrenal Hypoplasia Type 2 Diabetes Heart Attacks

Analogy Think of Bruce Banner (the Hulk) as Progesterone and Tony Stark (Iron man) as Estrogen...

The partnership between the HULK & Tony Stark.

Bibliography for Progesterone Burch, Candace. "Know Your Hormones." Your Hormone Balance. 10 Feb. 2014 <http://yourhormonebalance.com/hormone-balance-basics/know-your-hormones/#progesterone>. "NW Integrative Medicine." Signs of Hormone Imbalance. 11 Feb. 2014 <http://www.nwhealthcare.net/index.php?id=49>. "Progesterone | Progestin | HealthyWomen." Progesterone | Progestin | HealthyWomen. 10 Feb. 2014 <http://www.healthywomen.org/condition/progesterone>. "Progesterone (hormone)." Encyclopedia Britannica Online. Encyclopedia Britannica. 10 Feb. 2014 <http://www.britannica.com/EBchecked/topic/478202/progesterone>. "You & Your Hormones." You & Your Hormones. Jan. 2012. 10 Feb. 2014 <http://www.yourhormones.info/hormones/progesterone.aspx>. "The Effects of Hormones on Mood." The Effects of Hormones on Mood. 11 Feb. 2014 Bibliography for Estrogen "Endocrine System Information." Endocrine System Information. N.p., n.d. Web. 10 Feb. 2014. <http://www.pennmedicine.org/health_info/body_guide/reftext/html/endo_sys_fin.html>. "Hormones of the Reproductive System." Hormones of the Reproductive System. N.p., n.d. Web. 10 Feb. 2014. <http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/S/SexHormones.html>. "e.hormone | The Hormones : Estrogens." e.hormone | The Hormones : Estrogens. N.p., n.d. Web. 11 Feb. 2014. <http://e.hormone.tulane.edu/learning/estrogens.html>. http://www.intechopen.com/download/get/type/pdfs/id/22058 NMS OBSTETRICS AND GYNECOLOGY TEXTBOOK

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