Complications of Percutaneous Bone Tumor Cryoablation: A 10-year Experience Bone tumor cryoablation had a major complication rate of a 2.5%. The most frequent major complication of bone tumor cryoablation was secondary fracture, occurring in approximately 1.2% of patients. Major complications were seven times more likely to occur in older patients (>70 years) and over 20 times more likely when more than three cryoprobes are used. Auloge P et al. Published Online: Feb 26, 2019 https://doi.org/10.1148/radiol.2019181262 76-year-old man with a history of esophageal cancer show cryo-ablation of an iliac wing metastasis.