Ulf Lockowandt, MD, Anders Franco-Cereceda, MD, PhD

Slides:

Advertisements

Similar presentations

Angiographic predictors of graft patency and disease progression after coronary artery bypass grafting with arterial and venous grafts Hannu I Manninen,

Advertisements

Early postoperative outcome and medium-term survival in 540 diabetic and 2239 nondiabetic patients undergoing coronary artery bypass grafting Zoltán.

Coronary Artery Bypass for Heart Failure in Ischemic Cardiomyopathy: 17-Year Follow- Up Marco Pocar, MD, PhD, Andrea Moneta, MD, Adalberto Grossi, MD,

Leena Khaitan, MD, Francis P Sutter, Scott M Goldman, MD

Petar M. Vuković, MD, Sandra S. Radak, MD, Miodrag S

Detection of Postoperative Cognitive Decline After Coronary Artery Bypass Graft Surgery is Affected by the Number of Neuropsychological Tests in the Assessment.

Hospital readmission after coronary artery bypass grafting: are women doing worse? Johnny Steuer, MD, Paul Blomqvist, MD, PhD, Fredrik Granath, PhD, Bo.

Revascularization of severe hibernating myocardium in the beating heart: early hemodynamic and metabolic features Evasio Pasini, MD, Gianna Ferrari,

C-Reactive Protein Predicts Acute Kidney Injury and Death After Coronary Artery Bypass Grafting Seung Seok Han, MD, PhD, Dong Ki Kim, MD, PhD, Sejoong.

Coronary artery bypass grafting in patients with advanced left ventricular dysfunction Gregory D Trachiotis, MD, William S Weintraub, MD, Thomas S Johnston,

Angiographic predictors of graft patency and disease progression after coronary artery bypass grafting with arterial and venous grafts Hannu I Manninen,

Preoperative Aspirin Use and Its Effect on Adverse Events in Patients Undergoing Cardiac Operations Jiapeng Huang, MD, PhD, Macarius Donneyong, PhD,

Thomas V Bilfinger, MD, George B Stefano, PhD

Monocyte Fc gamma receptor expression in patients undergoing coronary artery bypass grafting Demetrios C Stefanou, FRCS, George Asimakopoulos, FRCS,

Long-Term Consequences of Postoperative Heart Failure After Surgery for Aortic Stenosis Compared With Coronary Surgery Farkas B. Vánky, MD, PhD, Erik.

Mortality and reoperations in survivors operated on for acute type A aortic dissection and implications for catheter-based or hybrid interventions Christian.

Evidence of Nitric Oxide Produced by the Internal Mammary Artery Graft in Venous Drainage of the Recipient Coronary Artery Ferenc I. Tarr, MD, PhD, Mária.

Mortality on the waiting list for coronary artery bypass grafting: incidence and risk factors Helena Rexius, MD, Gunnar Brandrup-Wognsen, MD, PhD, Anders.

CTSNet: a unique educational vehicle

Functional assessment of disease-free saphenous vein grafts at redo coronary artery bypass grafting Thomas V Bilfinger, MD, James A Vosswinkel, MD, Christos.

The Society of Thoracic Surgeons Thoracic Surgery Practice and Access Task Force: 2014 Workforce Report John S. Ikonomidis, MD, PhD The Annals of Thoracic.

Lindsay C.H. John, MD, FRCS The Annals of Thoracic Surgery

Perfusion-assisted direct coronary artery bypass: selective graft perfusion in off-pump cases Robert A Guyton, MD, Vinod H Thourani, MD, John D Puskas,

Coronary artery operation in patients after breast cancer therapy

Richard Gitter, Chris M. Cate, Kenneth Smart, G.Kimble Jett

Chronic Atrial Fibrillation Is Associated With Reduced Survival After Aortic and Double Valve Replacement Richard Schulenberg, MD, Polychronis Antonitsis,

Simple Index to Predict Likelihood of Skilled Nursing Facility Admission After Coronary Artery Bypass Grafting Among Older Patients David C. Chang, PhD,

Multilevel data analysis: What? Why? How?

Safe Coronary Artery Occlusion With a New Tourniquet in Off-Pump Bypass Grafting Hirokuni Arai, MD, PhD, Keiji Oi, MD, Hiroyuki Tanaka, MD, PhD, Noriyuki.

Mariano E. Brizzio, MD, Alex Zapolanski, MD, Richard E

Comparison of bovine and porcine heparin in heparin antibody formation after cardiac surgery John L Francis, PhD, George J Palmer, MD, Rebecca Moroose,

Coronary artery bypass on the beating heart with the Octopus: a North American experience1 Ted H Spooner, MD, Peter E Dyrud, MD, Bjorn K Monson, MD,

Cardiogenic shock due to coronary narrowings one day after a MAZE III procedure Eric Berreklouw, MD, PhD, Frank Bracke, MD, Albert Meijer, MD, PhD, Kathinka.

Surgical economics: MACRA, MIPS, and bundles—Lessons learned in the first 3 years of a coronary artery bypass grafting alternative payment model Daniel.

Hannu J Penttilä, MD, Martti V

Safety and efficacy of perioperative cell salvage and autotransfusion after coronary artery bypass grafting: a randomized trial Gavin J Murphy, MD, FRCS,

Reperfusion injury associated with one-fourth of deaths after coronary artery bypass grafting Saara M Weman, MD, Pekka J Karhunen, MD, Antti Penttilä,

Expression of Endothelin-1 and Constitutional Nitric Oxide Synthase Messenger RNA in Saphenous Vein Endothelial Cells Exposed to Arterial Flow Shear Stress

Pathology of the Radial and Internal Thoracic Arteries Used as Coronary Artery Bypass Grafts Eric Kaufer, BS, Stephen M Factor, MD, Rosemary Frame, MS,

Effect of blood transfusion on long-term survival after cardiac operation Milo C Engoren, MD, Robert H Habib, PhD, Anoar Zacharias, MD, Thomas A Schwann,

Application of cabrol technique to off-pump coronary artery bypass grafting using radial artery Won-Min Jo, MD, Chan-Young Na, MD, PhD, Man-Jong Baek,

Aortic Valve Replacement for Patients With Severe Aortic Stenosis: Risk Factors and Their Impact on 30-Month Mortality Edward L. Hannan, PhD, Zaza Samadashvili,

Tissue concentrations of endothelins and functional effects of endothelin-receptor activation in human arteries and veins Peter Holm, MD, Anders Franco-Cereceda,

Statin in Combination With β-Blocker Therapy Reduces Postoperative Stroke After Coronary Artery Bypass Graft Surgery Denis Bouchard, MD, Michel Carrier,

Early and Midterm Results of Off-Pump Coronary Artery Bypass Grafting

Limitations of Hospital Volume as a Measure of Quality of Care for Coronary Artery Bypass Graft Surgery Karl F. Welke, MD, Mitchell J. Barnett, PharmD,

Survival After Isolated Coronary Artery Bypass Grafting in Patients With Severe Left Ventricular Dysfunction Waleed A. Ahmed, MD, Phillip J. Tully, BHSc(Hons),

Isabella Rohrer-Gubler, Urs Niederhauser, Marko I Turina

First Report on 30-day and Operative Mortality in Risk Model of Isolated Coronary Artery Bypass Grafting in Japan Noboru Motomura, MD, PhD, Hiroaki Miyata,

Valvular heart operation is an independent risk factor for acute renal failure Antony D Grayson, Magdy Khater, FRCA, Mark Jackson, PhD, Mark A Fox, FRCA

Graft to Coronary Artery Shunt During Off-Pump Coronary Artery Bypass Grafting Hiroshi Iida, MD, PhD, Hideaki Mori, MD, PhD, Yoshio Sudo, MD, PhD, Yasuyuki.

Total Arterial Off-Pump Coronary Surgery: Time to Change Our Habits?

Kagami Miyaji, MD, Randall K Wolf, MD, John B Flege, MD

Adam E Saltman, MD, PhD, Walter H Dzik, MD, Sidney Levitsky, MD

Randomized Controlled Trial of Pericardial Blood Processing With a Cell-Saving Device on Neurologic Markers in Elderly Patients Undergoing Coronary Artery.

Measuring for improvement: from Toyota to thoracic surgery

Minimally invasive direct coronary artery bypass in a cardiac transplant recipient with allograft vasculopathy Ivan Aleksic, MD, PhD, Jarowit A Piotrowski,

Max B. Mitchell, MD, David N. Campbell, MD

Computer-assisted endoscopic coronary artery bypass anastomoses: a chronic animal study Edward R Stephenson, MD, Christopher T Ducko, MD, Sachin Sankholkar,

Coronary bypass flow during use of intraaortic balloon pumping and left ventricular assist device Takeo Tedoriya, MD, Michio Kawasuji, MD, Naoki Sakakibara,

Sérgio A de Oliveira, MD The Annals of Thoracic Surgery

Håvard Nordgaard, MD, Nicola Vitale, MD, PhD, Rune Haaverstad, MD, PhD

The endothelin antagonist BQ123 reduces pulmonary vascular resistance after surgical intervention for congenital heart disease Ingram Schulze-Neick,

Predicting Early Coronary Artery Bypass Graft Failure by Intraoperative Transit Time Flow Measurement Yoshiyuki Tokuda, MD, Min-Ho Song, MD, PhD, Yuichi.

Prevention of radial artery graft vasospasm after coronary bypass

Off-pump grafting of the main circumflex coronary artery in the atrioventricular groove via sternotomy Thomas A Vassiliades, MD The Annals of Thoracic.

Increased Rehospitalization Rate After Coronary Bypass Operation for Acute Coronary Syndrome: A Prospective Study in 200 Patients Staffan Bjessmo, MD,

Pulmonary artery banding before Norwood procedure

Dumbor L. Ngaage, MD, FRCS (C-Th), Michael E. Cowen, FRCS

Utilization and Outcomes of Unprotected Left Main Coronary Artery Stenting and Coronary Artery Bypass Graft Surgery Chuntao Wu, MD, PhD, Edward L. Hannan,

Presentation transcript:

Is there a role for endothelin-blockade early after coronary artery bypass grafting? Ulf Lockowandt, MD, Anders Franco-Cereceda, MD, PhD The Annals of Thoracic Surgery Volume 74, Issue 3, Pages 727-732 (September 2002) DOI: 10.1016/S0003-4975(02)03709-8

Fig 1 (a) Schematic illustration of the experimental protocol in group I (vehicle only for 10 minutes), group II (BQ-123, 260 nmol/min for 10 minutes), and group IV (BQ-123 and BQ-788, 260 and 250 nmol/min, respectively, for 10 minutes). Solid arrow = flow and hemodynamic registration; dashed arrow = blood samples. (b) Schematic illustration of the experimental protocol in group III (BQ-123, 260 nmol/min for 30 minutes) and group V (BQ-123 and BQ-788, 260 and 250 nmol/min, respectively, for 30 minutes). (ACh = acetylcholine; ADO = adenosine.) The Annals of Thoracic Surgery 2002 74, 727-732DOI: (10.1016/S0003-4975(02)03709-8)

Fig 2 (A) Coronary blood flow indirectly measured as vein graft flow after infusions in group I (vehicle only for 10 minutes), group II (BQ-123, 260 nmol/min for 10 minutes), and group IV (BQ-123 and BQ-788, 260 and 250 nmol/min, respectively, for 10 minutes). Values are given as means ± SD. (B) Coronary blood flow indirectly measured as vein graft flow after infusions in group III (BQ-123, 260 nmol/min for 30 minutes) and group V (BQ-123 and BQ-788, 260 and 250 nmol/min, respectively, for 30 minutes). Values are given as means ± SD. The Annals of Thoracic Surgery 2002 74, 727-732DOI: (10.1016/S0003-4975(02)03709-8)

Fig 3 Coronary blood flow indirectly measured as vein graft flow after infusion of acetylcholine (ACh) and adenosine (ADO). Group I (0.9% NaCl only; 1 mL/min for 10 minutes), group II (endothelina blocker BQ-123; 260 nmol/min for 10 minutes), group III (endothelina blocker BQ-123 in combination with endothelinb blocker BQ-788; 260 and 250 nmol/min, respectively, for 10 minutes), group IV (BQ-123; 260 nmol/min for 30 minutes), and group V (BQ-123 in combination with BQ-788; 260 and 250 nmol/min, respectively, for 30 minutes). For significance, see text. Values are given as means ± SD. The Annals of Thoracic Surgery 2002 74, 727-732DOI: (10.1016/S0003-4975(02)03709-8)