The Uncertain Significance of Anti–Glomerular Basement Membrane Antibody Among HIV-Infected Persons With Kidney Disease  Lynda Anne Szczech, MD, MSCE, Albert Anderson, MD, Christian Ramers, MD, John Engeman, MD, Matthew Ellis, MD, David Butterly, MD, David N. Howell, MD  American Journal of Kidney Diseases  Volume 48, Issue 4, Pages e55-e59 (October 2006) DOI: 10.1053/j.ajkd.2006.06.007 Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

Fig 1 Representative stains for the kidney biopsy specimen of patient 3. (A) Hematoxylin and eosin stain of a glomerulus shows membranous glomerulopathy. Note the lack of hypercellularity, crescent formation, or epithelial cell hyperplasia. (B) Periodic acid–Schiff stain of a glomerulus shows membranous glomerulopathy. (C) Immunofluorescence stain of a glomerulus shows nonlinear heterogeneous distribution of antibody more consistent with preexisting membranous and not consistent with the linear “ribbon-like” staining expected in anti-GBM disease. (D) Electron microscopy of a glomerulus shows subepithelial immune deposits with spiking of basement membrane consistent with membranous nephropathy. American Journal of Kidney Diseases 2006 48, e55-e59DOI: (10.1053/j.ajkd.2006.06.007) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions