Meiotic Recombination: Genetics’ Good Old Scalpel

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Meiotic Recombination: Genetics’ Good Old Scalpel Shai Slomka, Yitzhak Pilpel Cell Volume 172, Issue 3, Pages 391-392 (January 2018) DOI: 10.1016/j.cell.2018.01.017 Copyright © 2018 Elsevier Inc. Terms and Conditions

Figure 1 A Pipeline for the Discovery, Mapping, and Characterization of Genetic Determinants of Phenotypic Traits Two wild yeast strains are inbred for six generations. More than a thousand offspring are collected, which feature recombination between multiple sites of variation. Recombined progenies are phenotyped, genotype-phenotype associations are established for single-nucleotide variants, and causative mutations are assessed at single-gene and -protein levels and at the genetic network level. Cell 2018 172, 391-392DOI: (10.1016/j.cell.2018.01.017) Copyright © 2018 Elsevier Inc. Terms and Conditions