Immune evasion cluster-positive bacteriophages are highly prevalent among human Staphylococcus aureus strains, but they are not essential in the first.

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Presentation transcript:

Immune evasion cluster-positive bacteriophages are highly prevalent among human Staphylococcus aureus strains, but they are not essential in the first stages of nasal colonization N.J. Verkaik, M. Benard, H.A. Boelens, C.P. de Vogel, J.L. Nouwen, H.A. Verbrugh, D.C. Melles, A. van Belkum, W.J.B. van Wamel Clinical Microbiology and Infection Volume 17, Issue 3, Pages 343-348 (March 2011) DOI: 10.1111/j.1469-0691.2010.03227.x Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 1 Kaplan–Meier survival curves showing proportions of individuals with culture-positive nasal swab samples after artificial nasal inoculation of Staphylococcus aureus strain NCTC 8325–4 with or without immune evasion cluster (IEC)-carrying bacteriophage. Clinical Microbiology and Infection 2011 17, 343-348DOI: (10.1111/j.1469-0691.2010.03227.x) Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 2 Bacterial counts after artificial inoculation. Each dot represents the amount of CFUs in a nasal swab culture of a volunteer collected 1, 2, 3, 4, 7, 14, 21 and 28 days after artificial nasal inoculation of Staphylococcus aureus strain NCTC 8325–4 with or without immune evasion cluster (IEC)-carrying bacteriophage. Horizontal lines represent the median number of CFUs. Clinical Microbiology and Infection 2011 17, 343-348DOI: (10.1111/j.1469-0691.2010.03227.x) Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions