A MicroRNA-Based Test Improves Endoscopic Ultrasound–Guided Cytologic Diagnosis of Pancreatic Cancer  Randall E. Brand, Alex T. Adai, Barbara A. Centeno, Linda S. Lee, George Rateb, Shivakumar Vignesh, Charles Menard, Anna Wiechowska–Kozłowska, Hubert Bołdys, Marek Hartleb, Michael K. Sanders, Johanna B. Munding, Andrea Tannapfel, Stephan A. Hahn, Ludomir Stefańczyk, Gregory J. Tsongalis, David C. Whitcomb, Darwin L. Conwell, Jean A. Morisset, Timothy B. Gardner, Stuart R. Gordon, Arief A. Suriawinata, Maura B. Lloyd, Dennis Wylie, Emmanuel Labourier, Bernard F. Andruss, Anna E. Szafranska– Schwarzbach  Clinical Gastroenterology and Hepatology  Volume 12, Issue 10, Pages 1717-1723 (October 2014) DOI: 10.1016/j.cgh.2014.02.038 Copyright © 2014 AGA Institute Terms and Conditions

Figure 1 Overview of the development and clinical validation of the 5-miRNA classifier. Clinical Gastroenterology and Hepatology 2014 12, 1717-1723DOI: (10.1016/j.cgh.2014.02.038) Copyright © 2014 AGA Institute Terms and Conditions

Figure 2 Correlation between cytology, molecular scores, and final diagnoses for the 228 eligible study subjects. AAC, ampullary adenocarcinoma; AdenoCA, adenocarcinoma; CC, cholangiocarcinoma; indeterminate, atypical + suspicious; SCC, squamous cell carcinoma. Clinical Gastroenterology and Hepatology 2014 12, 1717-1723DOI: (10.1016/j.cgh.2014.02.038) Copyright © 2014 AGA Institute Terms and Conditions

Figure 3 Proposed integration of the 5-miRNA classifier into the current clinical management of patients with pancreatic solid masses. *Optimal patient management should be determined by a physician using available clinical information and 5-miRNA classifier testing results. Clinical Gastroenterology and Hepatology 2014 12, 1717-1723DOI: (10.1016/j.cgh.2014.02.038) Copyright © 2014 AGA Institute Terms and Conditions

Supplementary Figure 1 Clinical Gastroenterology and Hepatology 2014 12, 1717-1723DOI: (10.1016/j.cgh.2014.02.038) Copyright © 2014 AGA Institute Terms and Conditions

Supplementary Figure 2 Clinical Gastroenterology and Hepatology 2014 12, 1717-1723DOI: (10.1016/j.cgh.2014.02.038) Copyright © 2014 AGA Institute Terms and Conditions

Supplementary Figure 3 Clinical Gastroenterology and Hepatology 2014 12, 1717-1723DOI: (10.1016/j.cgh.2014.02.038) Copyright © 2014 AGA Institute Terms and Conditions

Supplementary Figure 4 Clinical Gastroenterology and Hepatology 2014 12, 1717-1723DOI: (10.1016/j.cgh.2014.02.038) Copyright © 2014 AGA Institute Terms and Conditions

Supplementary Figure 5 Clinical Gastroenterology and Hepatology 2014 12, 1717-1723DOI: (10.1016/j.cgh.2014.02.038) Copyright © 2014 AGA Institute Terms and Conditions