Andreas Herrlich, Eirini Kefaloyianni

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Presentation transcript:

iRhoms: A Potential Path to More Specific Therapeutic Targeting of Lupus Nephritis Andreas Herrlich, Eirini Kefaloyianni American Journal of Kidney Diseases Volume 72, Issue 4, Pages 617-619 (October 2018) DOI: 10.1053/j.ajkd.2018.04.010 Copyright © 2018 National Kidney Foundation, Inc. Terms and Conditions

Figure 1 Effects of iRhom2 knockout on lupus nephritis. iRhom2 acts downstream of the initial glomerular damage by immunecomplex deposition in LN. Some of its roles can be mimicked with inhibition of EGFR or TNFα. American Journal of Kidney Diseases 2018 72, 617-619DOI: (10.1053/j.ajkd.2018.04.010) Copyright © 2018 National Kidney Foundation, Inc. Terms and Conditions