Wearable Sensor-Based Biofeedback Training for Balance and Gait in Parkinson Disease: A Pilot Randomized Controlled Trial Ilaria Carpinella, MSc, Davide.

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Wearable Sensor-Based Biofeedback Training for Balance and Gait in Parkinson Disease: A Pilot Randomized Controlled Trial Ilaria Carpinella, MSc, Davide Cattaneo, PhD, Gianluca Bonora, PhD, Thomas Bowman, BSc, Laura Martina, MSc, Angelo Montesano, MD, Maurizio Ferrarin, PhD Archives of Physical Medicine and Rehabilitation Volume 98, Issue 4, Pages 622-630.e3 (April 2017) DOI: 10.1016/j.apmr.2016.11.003 Copyright © 2016 American Congress of Rehabilitation Medicine Terms and Conditions

Fig 1 Flowchart of the trial. Archives of Physical Medicine and Rehabilitation 2017 98, 622-630.e3DOI: (10.1016/j.apmr.2016.11.003) Copyright © 2016 American Congress of Rehabilitation Medicine Terms and Conditions

Fig 2 (A) Schematic representation of the Gamepad system. (B) Example of a subject controlling the AP inclination of his trunk while placing a foot on a step (left panel). The patient performs the task by looking at an avatar replicating the motion of his trunk on the PC screen (right panels). If the avatar is not maintained within the black bar (tailored reference target area), its head becomes red and an alarm sound is provided. Abbreviation: TMA sensor, Tecnobody Motion Analysis inertial sensor. Archives of Physical Medicine and Rehabilitation 2017 98, 622-630.e3DOI: (10.1016/j.apmr.2016.11.003) Copyright © 2016 American Congress of Rehabilitation Medicine Terms and Conditions

Supplemental Fig S1 Example of visual feedback provided by Gamepad. The vertical bar represents the knee flexion/extension angle. The bar is red in case of excessive knee flexion (left panel), whereas it turns green in case of adequate knee extension (right panel). Archives of Physical Medicine and Rehabilitation 2017 98, 622-630.e3DOI: (10.1016/j.apmr.2016.11.003) Copyright © 2016 American Congress of Rehabilitation Medicine Terms and Conditions

Supplemental Fig S2 Example of visual feedback provided by Gamepad. The circle represents the CoM that has to be moved from a starting position (START rectangle) to a final target position (yellow rectangle) toward the left (supporting) leg. The circle is green if the CoM in maintained within the target area, otherwise it turns red. Abbreviation: CoM, center of mass. Archives of Physical Medicine and Rehabilitation 2017 98, 622-630.e3DOI: (10.1016/j.apmr.2016.11.003) Copyright © 2016 American Congress of Rehabilitation Medicine Terms and Conditions