Increasing duration of circulatory arrest, but not antegrade cerebral perfusion, prolongs postoperative recovery after neonatal cardiac surgery Selma.

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Presentation transcript:

Increasing duration of circulatory arrest, but not antegrade cerebral perfusion, prolongs postoperative recovery after neonatal cardiac surgery Selma O. Algra, MD, Verena N.N. Kornmann, MD, Ingeborg van der Tweel, PhD, Antonius N.J. Schouten, MD, Nicolaas J.G. Jansen, MD, Felix Haas, MD The Journal of Thoracic and Cardiovascular Surgery Volume 143, Issue 2, Pages 375-382 (February 2012) DOI: 10.1016/j.jtcvs.2011.08.006 Copyright © 2012 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Linear regression of log-transformed ICU-LOS, n = 76. ICU-LOS, Length of stay in intensive care unit; DHCA, deep hypothermic circulatory arrest; ACP, antegrade cerebral perfusion; b, regression coefficient; CI, confidence interval; R, correlation coefficient; R2, determination coefficient; CPB, cardiopulmonary bypass; n.s., not significant; n.t., not tested; ∗P < .05; ∗∗P < .005. The Journal of Thoracic and Cardiovascular Surgery 2012 143, 375-382DOI: (10.1016/j.jtcvs.2011.08.006) Copyright © 2012 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Linear regression of log-transformed duration of mechanical ventilation, n = 78. DHCA, Deep hypothermic circulatory arrest; ACP, antegrade cerebral perfusion; b, regression coefficient; CI, confidence interval; R, correlation coefficient; R2, determination coefficient; CPB, cardiopulmonary bypass; n.s., not significant; n.t., not tested; ∗∗P < .005. The Journal of Thoracic and Cardiovascular Surgery 2012 143, 375-382DOI: (10.1016/j.jtcvs.2011.08.006) Copyright © 2012 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Linear regression of log-transformed AUC of lactate >2.5 mmol/L, n = 81. AUC, Area under the curve; DHCA, deep hypothermic circulatory arrest; ACP, antegrade cerebral perfusion; b, regression coefficient; CI, confidence interval; R, correlation coefficient; R2, determination coefficient; CPB, cardiopulmonary bypass; n.s., not significant; n t., not tested; ∗∗P < .005. The Journal of Thoracic and Cardiovascular Surgery 2012 143, 375-382DOI: (10.1016/j.jtcvs.2011.08.006) Copyright © 2012 The American Association for Thoracic Surgery Terms and Conditions

Figure 4 Linear regression of log-transformed AUC of creatinine above baseline, n = 80. AUC, Area under the curve; DHCA, deep hypothermic circulatory arrest; ACP, antegrade cerebral perfusion; b, regression coefficient; CI, confidence interval; R, correlation coefficient; R2, determination coefficient; CPB, cardiopulmonary bypass; n.s., not significant; n.t., not tested; ∗∗P < .005. The Journal of Thoracic and Cardiovascular Surgery 2012 143, 375-382DOI: (10.1016/j.jtcvs.2011.08.006) Copyright © 2012 The American Association for Thoracic Surgery Terms and Conditions