A. Dyson, S. Cone, M. Singer, G.L. Ackland

Slides:

Advertisements

Similar presentations

Blockade of spinal nerves inhibits expression of neural growth factor in the myocardium at an early stage of acute myocardial infarction in rats W. Yue,

Advertisements

F. Chung, R. Subramanyam, P. Liao, E. Sasaki, C. Shapiro, Y. Sun

Randomized controlled trial comparing the McGrath videolaryngoscope with the C-MAC videolaryngoscope in intubating adult patients with potential difficult.

Pain in cancer survivors; filling in the gaps

E. Langesæter, L.A. Rosseland, A. Stubhaug

R. Kaw, F. Chung, V. Pasupuleti, J. Mehta, P.C. Gay, A.V. Hernandez

Treatment of pulmonary hypertension in the general adult intensive care unit: a role for oral sildenafil? J Ng, S.J. Finney, R Shulman, G.J. Bellingan,

Bispectral index-guided induction of general anaesthesia in patients undergoing major abdominal surgery using propofol or etomidate: a double-blind, randomized,

Gut microcirculatory and mitochondrial effects of hyperdynamic endotoxaemic shock and norepinephrine treatment A. Andersson, M. Rundgren, S. Kalman,

Fluid responsiveness: an evolution of our understanding

Coronary artery bypass grafting in the awake patient combining high thoracic epidural and femoral nerve block: first series of 15 patients N. Noiseux,

Lidocaine use in ultrasound-guided femoral nerve block: what is the minimum effective anaesthetic concentration (MEAC90)?† A.M. Taha, A.M. Abd-Elmaksoud

K.-Y. Ho, W Tay, M.-C. Yeo, H Liu, S.-J. Yeo, S.-L. Chia, N.-N. Lo

High concordance between expert anaesthetists’ actions and advice of decision support system in achieving oxygen delivery targets in high-risk surgery.

Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs for the reduction in morphine-related side-effects after major surgery:

Orthostatic function and the cardiovascular response to early mobilization after breast cancer surgery R.G. Müller, M. Bundgaard-Nielsen, H. Kehlet

Randomized controlled trial of goal-directed haemodynamic treatment in patients with proximal femoral fracture E. Bartha, C. Arfwedson, A. Imnell, M.E.

Nitrous oxide exposure does not seem to be associated with increased mortality, stroke, and myocardial infarction: a non-randomized subgroup analysis.

Perioperative statin therapy in patients at high risk for cardiovascular morbidity undergoing surgery: a review B.A. de Waal, M.P. Buise, A.A.J. van.

Expression of the nociceptin precursor and nociceptin receptor is modulated in cancer and septic patients U.M. Stamer, M. Book, C. Comos, L. Zhang, F.

T. Ledowski, J. Burke, J. Hruby British Journal of Anaesthesia

Does motor block related to long-acting brachial plexus block cause patient dissatisfaction after minor wrist and hand surgery? A randomized observer-blinded.

Ultrasound visual image-guided vs Doppler auditory-assisted radial artery cannulation in infants and small children by non-expert anaesthesiologists:

Preoperative supplementation with fibrinogen concentrate in cardiac surgery: A randomized controlled study A. Jeppsson, K. Waldén, C. Roman-Emanuel,

Assessing fluid responsiveness during open chest conditions

Effects of cardiopulmonary bypass on neurocognitive performance and cytokine release in old and diabetic rats F. de Lange, J.M. Dieleman, B. Jungwirth,

Raised serum cardiac troponin I concentrations predict hospital mortality in intensive care unit patients† T. Reynolds, M. Cecconi, P. Collinson, A.

Measuring quality of recovery-15 after day case surgery

Preadmission statin use improves the outcome of less severe sepsis patients - a population-based propensity score matched cohort study M.G. Lee, C.-C.

C.C. Jørgensen, H. Kehlet British Journal of Anaesthesia

A. A. Klein, T. Collier, J. Yeates, L. F. Miles, S. N. Fletcher, C

Continuous and minimally invasive cardiac output monitoring by long time interval analysis of a radial arterial pressure waveform: assessment using a.

Evaluation of the effect of intravenous lidocaine on propofol requirements during total intravenous anaesthesia as measured by bispectral index† F.R.

Supplemental intravenous crystalloids for the prevention of postoperative nausea and vomiting: quantitative review C.C. Apfel, A. Meyer, M. Orhan-Sungur,

A. Dyson, N. Ekbal, M. Stotz, S. Barnes, J. Carré, S. Tully, S

M. Iwata, S. Inoue, M. Kawaguchi, H. Furuya

Do team processes really have an effect on clinical performance

Safety culture and the 5 steps to safer surgery: an intervention study

A. Abdelnasser, B. Abdelhamid, A. Elsonbaty, A. Hasanin, A. Rady

Incidence of postoperative nausea and vomiting after paediatric strabismus surgery with sevoflurane or remifentanil–sevoflurane A.Y. Oh, J.H. Kim, J.W.

Ultrasound-assisted spinal anaesthesia in a patient with Wildervanck syndrome and congenital abnormalities of the lumbar spine T. Schisler, H. Huttunen,

Preoperative evaluation of patients with, or at risk of, coronary artery disease undergoing non-cardiac surgery P.-G. Chassot, A. Delabays, D.R. Spahn

S Singh, J.E. Smith British Journal of Anaesthesia

Distraction and interruption in anaesthetic practice

Do old pharmacokinetic parameter estimates predict new data?

S.G. Sakka, K. Reinhart, A. Meier-Hellmann

Lung recruitment and positive airway pressure before extubation does not improve oxygenation in the post-anaesthesia care unit: a randomized clinical.

Reviewer Acknowledgment

Predictive value of pulse pressure variation for fluid responsiveness in septic patients using lung-protective ventilation strategies F.G.R. Freitas,

Visual metaphors on anaesthesia monitors do not improve anaesthetists' performance in the operating theatre K. van Amsterdam, F. Cnossen, A. Ballast,

Effects of oxytocin on Purkinje fibres

Corrigendum British Journal of Anaesthesia

Antioxidants that protect mitochondria reduce interleukin-6 and oxidative stress, improve mitochondrial function, and reduce biochemical markers of organ.

Influence of increased left ventricular myocardial mass on early and late mortality after cardiac surgery M.M. Weiner, D.L. Reich, H.M. Lin, M. Krol,

The effect of ephedrine on intubating conditions and haemodynamics during rapid tracheal intubation using propofol and rocuronium M.D. Gopalakrishna,

Association of sustained cardiovascular recovery with epinephrine in the delayed lipid- based resuscitation from cardiac arrest induced by bupivacaine.

Heterogeneity of studies in anesthesiology systematic reviews: a meta-epidemiological review and proposal for evidence mapping B. Umberham, R. Hedin,

Teamwork, communication, and anaesthetic assistance in Scotland

Combined paravertebral and intrathecal vs thoracic epidural analgesia for post- thoracotomy pain relief S. Dango, S. Harris, K. Offner, E. Hennings, H.-J.

Sepsis and the heart British Journal of Anaesthesia

A.J. Ross, N. Kodate, J.E. Anderson, L. Thomas, P. Jaye

Systematic review of the QoR-15 score, a patient- reported outcome measure measuring quality of recovery after surgery and anaesthesia J. Kleif, J. Waage,

Modern anaesthesia training: is it good enough?

T. W. Jones, D. Houghton, S. Cassidy, G. A. MacGowan, M. I. Trenell, D

Unconscious learning during surgery with propofol anaesthesia†

S.J. Olday, R. Walpole, J.Y.Y. Wang British Journal of Anaesthesia

Levosimendan pre-treatment improves outcomes in patients undergoing coronary artery bypass graft surgery† L. Tritapepe, V. De Santis, D. Vitale, F. Guarracino,

C.M. Chalmers, A.M. Bal British Journal of Anaesthesia

Effects of dexmedetomidine on adrenocortical function, and the cardiovascular, endocrine and inflammatory responses in post-operative patients needing.

R. Parke, S. McGuinness, R. Dixon, A. Jull

Presentation transcript:

Microvascular and macrovascular flow are uncoupled in early polymicrobial sepsis A. Dyson, S. Cone, M. Singer, G.L. Ackland British Journal of Anaesthesia Volume 108, Issue 6, Pages 973-978 (June 2012) DOI: 10.1093/bja/aes093 Copyright © 2012 The Author(s) Terms and Conditions

Fig 1 Macrovascular phenotype in naive, sham-operated, and septic rats. (a) Mean arterial pressure. (b) Heart rate. (c) Stroke volume. (d) Cardiac output. All data (measured at 6 h post-surgery) are displayed as median (IQR). *Difference (P<0.01; the Kruskal–Wallis test) between severe sepsis and other conditions; #Differences (P<0.01; the Kruskal–Wallis test) between naive and mild septic rats. British Journal of Anaesthesia 2012 108, 973-978DOI: (10.1093/bja/aes093) Copyright © 2012 The Author(s) Terms and Conditions

Fig 2 Microvascular phenotype in naive, sham-operated, and septic rats, measured at 6 h post-surgery. (a) Raw MFI scores in relation to stroke volume (R2=0.13; P=0.08; Spearman’s rank correlation test). (b) Microvascular flow heterogeneity index. (c) Perfused small-vessel density. (d) The De Backer score. Data displayed as (a) raw data, (b–d) [median (IQR)]. *Difference (P<0.05, the Kruskal–Wallis test) between naive and other treatment groups. British Journal of Anaesthesia 2012 108, 973-978DOI: (10.1093/bja/aes093) Copyright © 2012 The Author(s) Terms and Conditions