E. Bandak, M. Boesen, H. Bliddal, R. G. C. Riis, H. Gudbergsen, M

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Associations between muscle perfusion and symptoms in knee osteoarthritis: a cross sectional study E. Bandak, M. Boesen, H. Bliddal, R.G.C. Riis, H. Gudbergsen, M. Henriksen Osteoarthritis and Cartilage Volume 23, Issue 10, Pages 1721-1727 (October 2015) DOI: 10.1016/j.joca.2015.05.032 Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Maps of DCE-MRI perfusion variables in a representative patient with KOA. Axial DCE-MRI gradient echo (GRE) T1 w VIBE sequence approximately at the level of basis patella in a representative patient with KOA (A–D). A, The drawing of region of interests (ROIs) around of all the peri-articular knee muscles avoiding major vascular branches. B, Contrast Uptake Pattern: The voxels are automatically assigned and color coded in a Gadolinium (Gd)-enhancement map to one of the four enhancement patterns: washout (red), persistent (blue), plateau (green), or no enhancement (no color). C, maps of IRE, and D, maps of Maximum Enhancement (ME). Values of IRE and ME are color-coded and superimposed on the grey scale dynamic images. The highest values are shown in bright yellow to white and lower values in a spectrum of red colors. White arrows: The popliteal artery. Blue arrows: Enhancement in the synovium in the retro-patellar space. Osteoarthritis and Cartilage 2015 23, 1721-1727DOI: (10.1016/j.joca.2015.05.032) Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 Flowchart. Osteoarthritis and Cartilage 2015 23, 1721-1727DOI: (10.1016/j.joca.2015.05.032) Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions