Lobectomy for Non-Small Cell Lung Cancer by Video-Assisted Thoracic Surgery: Effects of Cumulative Institutional Experience on Adequacy of Lymphadenectomy

Slides:

Advertisements

Similar presentations

Thoracoscopic lobectomy is associated with lower morbidity than open lobectomy: A propensity-matched analysis from the STS database Subroto Paul, MD,

Advertisements

Elizabeth A. David, MD, David T

Jeffrey L. Port, MD, Robert J. Korst, MD, Paul C. Lee, MD, Amanda L

Outcomes of Major Lung Resection After Induction Therapy for Non-Small Cell Lung Cancer in Elderly Patients Chi-Fu Jeffrey Yang, MD, Nicholas R. Mayne,

Definitive or Preoperative Chemoradiation Therapy for Esophageal Cancer: Patterns of Care and Survival Outcomes Meng S. Shao, MD, Andrew T. Wong, MD,

A Propensity-Matched Analysis of Wedge Resection and Stereotactic Body Radiotherapy for Early Stage Lung Cancer Jeffrey L. Port, MD, Bhupesh Parashar,

Complete Thoracic Mediastinal Lymphadenectomy Leads to a Higher Rate of Pathologically Proven N2 Disease in Patients With Non-Small Cell Lung Cancer

Thomas J. Birdas, MD, Richard P. M

Number of Lymph Nodes and Metastatic Lymph Node Ratio Are Associated With Survival in Lung Cancer Chukwumere E. Nwogu, MD, Adrienne Groman, MA, Daniel.

Characteristics and outcomes of secondary nodules identified on initial computed tomography scan for patients undergoing resection for primary non–small.

Complete Metabolic Response Is Not Uniformly Predictive of Complete Pathologic Response After Induction Therapy for Esophageal Cancer Brendon M. Stiles,

Melanie Subramanian, MD, Timothy McMurry, PhD, Bryan F

Comparison of Thoracoscopic Segmentectomy and Thoracoscopic Lobectomy for Small-Sized Stage IA Lung Cancer Chenxi Zhong, MD, Wentao Fang, MD, Teng Mao,

Oncologic Outcomes of Segmentectomy Versus Lobectomy for Clinical T1a N0 M0 Non- Small Cell Lung Cancer Ken Kodama, MD, Masahiko Higashiyama, MD, Jiro.

Joshua E. Rosen, BASc, Hari B

Elliot Wakeam, MD, MPH, Meredith Giuliani, MBBS, MEd, Natasha B

Tumor Necrosis as a Prognostic Factor for Stage IA Non-Small Cell Lung Cancer Seong Yong Park, MD, Hyun-Sung Lee, MD, PhD, Hee-Jin Jang, MD, Geon Kook.

Lisa M. Brown, MD, MAS, David T. Cooke, MD, Elizabeth A. David, MD

Adjuvant Chemotherapy with 5-Fluorouracil and Cisplatin in Lymph Node-Positive Thoracic Esophageal Squamous Cell Carcinoma Jeeyun Lee, MD, Kyoung-Eun.

Long-Term Consequences of Postoperative Heart Failure After Surgery for Aortic Stenosis Compared With Coronary Surgery Farkas B. Vánky, MD, PhD, Erik.

Benjamin E. Lee, MD, Mark Shapiro, MD, John R. Rutledge, MAS, Robert J

Prevalence, outcomes, and a risk–benefit analysis of diaphragmatic hernia admissions: An examination of the National Inpatient Sample database Subroto.

Video-Assisted Thoracic Surgery Lobectomy: Experience With 1,100 Cases

Lobectomy in Octogenarians With Non-Small Cell Lung Cancer: Ramifications of Increasing Life Expectancy and the Benefits of Minimally Invasive Surgery

Lymph Node Evaluation by Open or Video-Assisted Approaches in 11,500 Anatomic Lung Cancer Resections Daniel J. Boffa, MD, Andrzej S. Kosinski, PhD, Subroto.

Clinical T2-T3N0M0 Esophageal Cancer: The Risk of Node Positive Disease Brendon M. Stiles, MD, Farooq Mirza, MD, Anthony Coppolino, MD, Jeffrey L. Port,

Lymph Node Evaluation Achieved by Open Lobectomy Compared With Thoracoscopic Lobectomy for N0 Lung Cancer Robert E. Merritt, MD, Chuong D. Hoang, MD,

Brendon M. Stiles, MD, Farooq Mirza, MD, Jeffrey L. Port, MD, Paul C

Surgical Treatment of Metachronous Second Primary Lung Cancer

Mohamed K. Kamel, MD, Mohamed Rahouma, MD, Benjamin Lee, MD, Sebron W

A Risk Score to Assist Selecting Lobectomy Versus Sublobar Resection for Early Stage Non-Small Cell Lung Cancer Brian C. Gulack, MD, Chi-Fu Jeffrey Yang,

Chris Dickhoff, MD, Max Dahele, MD, PhD, Sayed M

Survival of Patients With or Without Symptoms Undergoing Potentially Curative Resections for Primary Lung Cancer Andrea R.G. Sheel, BS (Hons), MBChB,

Pulmonary Resection in the Treatment of Multidrug-Resistant Tuberculosis: A Retrospective Study of 56 Cases Haifeng Wang, MM, Hongsheng Lin, MM, Gening.

Asad A. Shah, MD, Mathias Worni, MD, MHS, Christopher R

Improved Lymph Node Staging in Early-Stage Lung Cancer in the National Cancer Database Seth B. Krantz, MD, Waseem Lutfi, BS, Kristine Kuchta, MS, Chi-Hsiung.

Elliot Wakeam, MD, MPH, James P. Byrne, MD, Gail E

Predictors of recurrence and disease-free survival in patients with completely resected esophageal carcinoma Paul C. Lee, MD, Farooq M. Mirza, MD, Jeffrey.

Recurrence and Survival After Segmentectomy in Patients With Prior Lung Resection for Early-Stage Non-Small Cell Lung Cancer Lisa M. Brown, MD, Brian.

Brendon M. Stiles, MD, Mohamed K. Kamel, MD, Sebron W

Differences in Patterns of Recurrence in Early-Stage Versus Locally Advanced Non- Small Cell Lung Cancer Feiran Lou, MD, MS, Camelia S. Sima, MD, MS,

Predictors of Long-Term Survival After Resection of Esophageal Carcinoma With Nonregional Nodal Metastases Paul C. Lee, MD, Jeffrey L. Port, MD, Subroto.

PUB010 Intraoperative Blood Loss is an Independent Predictor of Poor Disease Free Survival for Patients Undergoing VATS Lobectomy for Lung Cancer M.

Video-Assisted Thoracoscopic Surgery is More Favorable Than Thoracotomy for Resection of Clinical Stage I Non-Small Cell Lung Cancer Bryan A. Whitson,

VATS Lobectomy Has Better Perioperative Outcomes Than Open Lobectomy: CALGB 31001, an Ancillary Analysis of CALGB (Alliance) Chukwumere E. Nwogu,

Extent of Lymphadenectomy Is Associated With Improved Overall Survival After Esophagectomy With or Without Induction Therapy Pamela Samson, MD, MPHS,

Selective Mediastinal Lymphadenectomy for Clinico-Surgical Stage I Non–Small Cell Lung Cancer Morihito Okada, MD, PhD, Toshihiko Sakamoto, MD, PhD, Tsuyoshi.

Lymph Node Assessment and Impact on Survival in Video-Assisted Thoracoscopic Lobectomy or Segmentectomy Haiyu Zhou, MD, Luis F. Tapias, MD, Henning A.

Surgical Treatment for Limited-Stage Primary Small Cell Cancer of the Esophagus Dongrong Situ, MD, Yongbin Lin, MD, PhD, Hao Long, MD, PhD, Lanjun Zhang,

Number of Metastatic Lymph Nodes in Resected Non–Small Cell Lung Cancer Predicts Patient Survival Jin Gu Lee, MD, Chang Young Lee, MD, In Kyu Park, MD,

Asvin M. Ganapathi, MD, Paul J. Speicher, MD, Anthony W

Arman Kilic, BS, Matthew J. Schuchert, MD, Brian L

Prevalence and Outcomes of Anatomic Lung Resection for Hemoptysis: An Analysis of the Nationwide Inpatient Sample Database Subroto Paul, MD, Weston Andrews,

The Annals of Thoracic Surgery

Adhering to Quality Measures in Esophagectomy Is Associated With Improved Survival in All Stages of Esophageal Cancer Pamela Samson, MD, MPHS, Varun.

Shared Decision Making and Effective Risk Communication in the High-Risk Patient With Operable Stage I Non-Small Cell Lung Cancer Pamela Samson, MD,

Galal Ghaly, MD, Sebron Harrison, MD, Mohamed K

Effects of Delayed Surgical Resection on Short-Term and Long-Term Outcomes in Clinical Stage I Non-Small Cell Lung Cancer Pamela Samson, MD, Aalok Patel,

Modern Outcome and Risk Analysis of Surgically Resected Occult N2 Non-Small Cell Lung Cancer Hyun Jin Cho, MD, Sung Ryong Kim, MD, Hyeong Ryul Kim, MD,

Relevance of Lymph Node Micrometastases in Radically Resected Endobronchial Carcinoid Tumors Tommaso Claudio Mineo, MD, Gianluca Guggino, MD, Davide.

Mert Saynak, MD, Jessica Hubbs, MS, Jiho Nam, MD, Lawrence B

Propensity Score Analysis Comparing Videothoracoscopic Lobectomy With Thoracotomy: A French Nationwide Study Pierre-Benoit Pagès, MD, PhD, Jean-Philippe.

Effect of Formalin Fixation on Tumor Size Determination in Stage I Non-Small Cell Lung Cancer Po-Kuei Hsu, MD, Hsu-Chih Huang, MD, Chih-Cheng Hsieh,

Predictors of Pleural Implants in Patients With Thymic Tumors

Clinical Outcome After Pulmonary Resection for Lung Cancer Patients on Hemodialysis Toshiro Obuchi, MD, Wakako Hamanaka, MD, Yasuhiro Yoshida, MD, Jun.

Survival and Outcomes of Pulmonary Resection for Non-Small Cell Lung Cancer in the Elderly: A Nested Case-Control Study Robert J. Cerfolio, MD, Ayesha.

Mark I. Block, MD The Annals of Thoracic Surgery

Early Surgical Results After Pneumonectomy for Non-Small Cell Lung Cancer are not Affected by Preoperative Radiotherapy and Chemotherapy Tomas Gudbjartsson,

Thoracoscopic lobectomy is associated with lower morbidity than open lobectomy: A propensity-matched analysis from the STS database Subroto Paul, MD,

Video-Assisted Thoracoscopic Surgery Is a Safe and Effective Alternative to Thoracotomy for Anatomical Segmentectomy in Patients With Clinical Stage I.

Presentation transcript:

Lobectomy for Non-Small Cell Lung Cancer by Video-Assisted Thoracic Surgery: Effects of Cumulative Institutional Experience on Adequacy of Lymphadenectomy Paul C. Lee, MD, Mohamed Kamel, MD, Abu Nasar, MS, Galal Ghaly, MD, Jeffrey L. Port, MD, Subroto Paul, MD, Brendon M. Stiles, MD, Weston G. Andrews, MD, Nasser K. Altorki, MD The Annals of Thoracic Surgery Volume 101, Issue 3, Pages 1116-1122 (March 2016) DOI: 10.1016/j.athoracsur.2015.09.073 Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 The percentage of lobectomies done by video-assisted thoracic surgery (VATS) at Weill Cornell Medical College is shown between 2002 and 2013. The Annals of Thoracic Surgery 2016 101, 1116-1122DOI: (10.1016/j.athoracsur.2015.09.073) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 A greater number of lymph nodes (LN; solid line) and nodal stations (dashed line) were excised during video-assisted thoracic surgery (VATS) lobectomy in (A) all patients and in (B) patients at clinical (c) stage IA as the cumulative institutional surgical volume increased. The Annals of Thoracic Surgery 2016 101, 1116-1122DOI: (10.1016/j.athoracsur.2015.09.073) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 In an effort to determine the learning curve of an individual surgeon in video-assisted thoracic surgery (VATS) lymphadenectomy, we analyzed the number of lymph nodes (black line) harvested from the first 100 cases done by the most senior surgeon in our institution (N.K.A.) The Annals of Thoracic Surgery 2016 101, 1116-1122DOI: (10.1016/j.athoracsur.2015.09.073) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Kaplan-Meier analysis of the propensity-matched groups showed no difference in disease-free survival, which was 82% in the early group (dashed line) vs 85% in the late group (solid line) at 3 years. The Annals of Thoracic Surgery 2016 101, 1116-1122DOI: (10.1016/j.athoracsur.2015.09.073) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions