Kasiani C. Myers, Stella M. Davies

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Presentation transcript:

Hematopoietic Stem Cell Transplantation for Bone Marrow Failure Syndromes in Children Kasiani C. Myers, Stella M. Davies Biology of Blood and Marrow Transplantation Volume 15, Issue 3, Pages 279-292 (March 2009) DOI: 10.1016/j.bbmt.2008.11.037 Copyright © 2009 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Survival after HLA-identical sibling donor BMT according to age. Probability of survival after HLA-identical sibling BMT for acquired AA is stratified by age at time of transplantation. Data obtained from the EBMT Register, Severe Aplastic Anemia Working Party, 2003. (Reprinted with permission [23].) Biology of Blood and Marrow Transplantation 2009 15, 279-292DOI: (10.1016/j.bbmt.2008.11.037) Copyright © 2009 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 Five-year survival in recipients of unrelated donor transplantations for severe AA before and after 1998. (Reprinted with permission [50].) Biology of Blood and Marrow Transplantation 2009 15, 279-292DOI: (10.1016/j.bbmt.2008.11.037) Copyright © 2009 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 3 Probability of overall survival of unrelated donor transplantation with fludarabine and nonfludarabine regimens in FA patients after adjusting for previous red blood cell transfusions and cytomegalovirus serostatus. (Reprinted with permission [63].) Biology of Blood and Marrow Transplantation 2009 15, 279-292DOI: (10.1016/j.bbmt.2008.11.037) Copyright © 2009 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 4 Survival of 93 FA patients who underwent UCBT according to the use of fludarabine in the conditioning regimen. (Reprinted with permission [90].) Biology of Blood and Marrow Transplantation 2009 15, 279-292DOI: (10.1016/j.bbmt.2008.11.037) Copyright © 2009 American Society for Blood and Marrow Transplantation Terms and Conditions