Volume 10, Issue 8, Pages (August 2017)

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Volume 10, Issue 8, Pages 1133-1136 (August 2017) WheatNet: a Genome-Scale Functional Network for Hexaploid Bread Wheat, Triticum aestivum Tak Lee, Sohyun Hwang, Chan Yeong Kim, Hongseok Shim, Hyojin Kim, Pamela C. Ronald, Edward M. Marcotte, Insuk Lee Molecular Plant Volume 10, Issue 8, Pages 1133-1136 (August 2017) DOI: 10.1016/j.molp.2017.04.006 Copyright © 2017 The Author Terms and Conditions

Figure 1 Overview of WheatNet. (A–D) Degree of connectivity (A) among 45 genes for response to Blumeria graminis f. sp. tritici infection and (B) among 17 genes for response to drought stress were measured by determining the number of edges among group members (i.e., within-group edge count) or the number of network neighbors that overlapped among group members (i.e., network neighbor overlap) by using WheatNet (red stars) or 1000 random gene sets having the same size (black circles). Largest components of networks of (C) the genes for response to B. graminis f. sp. tritici infection and (D) those for response to drought stress by WheatNet. (E) Results of gene prioritization by the direct neighborhood method. The top 100 candidate genes and associated Gene Ontology terms are listed in a table. In addition, the network of guide genes and candidate genes is shown. (F) The results of gene prioritization by the context-associated hub method. The top 100 predictions and associated Gene Ontology terms are listed in a table. By clicking each candidate gene, users can view a network composed of the hub gene and connected differentially expressed genes. Molecular Plant 2017 10, 1133-1136DOI: (10.1016/j.molp.2017.04.006) Copyright © 2017 The Author Terms and Conditions