The prevalence of food allergy and other allergic diseases in early childhood in a population-based study: HealthNuts age 4-year follow-up Rachel L.

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Presentation transcript:

The prevalence of food allergy and other allergic diseases in early childhood in a population-based study: HealthNuts age 4-year follow-up Rachel L. Peters, PhD, Jennifer J. Koplin, PhD, Lyle C. Gurrin, PhD, Shyamali C. Dharmage, MBBS, MSc, MD, PhD, Melissa Wake, MD, FRACP, Anne-Louise Ponsonby, MBBS, FAFPHM, FRACP, PhD, Mimi L.K. Tang, MBBS, PhD, FRACP, FRCPA, FAAAAI, Adrian J. Lowe, PhD, Melanie Matheson, PhD, Terence Dwyer, PhD, Katrina J. Allen, MBBS, BMedSc, FRACP, FAAAI, PhD Journal of Allergy and Clinical Immunology Volume 140, Issue 1, Pages 145-153.e8 (July 2017) DOI: 10.1016/j.jaci.2017.02.019 Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Participation in HealthNuts Wave 2, the age 4-year follow-up. Journal of Allergy and Clinical Immunology 2017 140, 145-153.e8DOI: (10.1016/j.jaci.2017.02.019) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 The prevalence of challenge-confirmed food allergy at age 1 and 4 years in a population-based cohort (n = 5276). Journal of Allergy and Clinical Immunology 2017 140, 145-153.e8DOI: (10.1016/j.jaci.2017.02.019) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 3 Number of allergic diseases experienced by children in the first 4 years of life for the whole cohort (n = 5276 which includes participants who are missing an outcome for 1 or more allergies, eg, by not participating in age 4-year follow-up) and those with complete data on all 4 allergies (n = 2907). Journal of Allergy and Clinical Immunology 2017 140, 145-153.e8DOI: (10.1016/j.jaci.2017.02.019) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 4 A, Venn diagram depicting the overlap of current allergic diseases in 1-year-old infants (the size of the circle is proportional to the outcome). B, Venn diagram depicting the overlap of current allergic disease in 4-year-old children (among those with complete data for all 3 variables; excluding allergic rhinitis). Journal of Allergy and Clinical Immunology 2017 140, 145-153.e8DOI: (10.1016/j.jaci.2017.02.019) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E1 Follow-up of participants who were food allergic at age 1 year: Assignment of definite, probable, and possible food allergy outcomes at age 4 years. A, Peanut. B, Egg. C, Sesame. neg, Negative; PPV, positive predictive value; pos, positive. Journal of Allergy and Clinical Immunology 2017 140, 145-153.e8DOI: (10.1016/j.jaci.2017.02.019) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E1 Follow-up of participants who were food allergic at age 1 year: Assignment of definite, probable, and possible food allergy outcomes at age 4 years. A, Peanut. B, Egg. C, Sesame. neg, Negative; PPV, positive predictive value; pos, positive. Journal of Allergy and Clinical Immunology 2017 140, 145-153.e8DOI: (10.1016/j.jaci.2017.02.019) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E1 Follow-up of participants who were food allergic at age 1 year: Assignment of definite, probable, and possible food allergy outcomes at age 4 years. A, Peanut. B, Egg. C, Sesame. neg, Negative; PPV, positive predictive value; pos, positive. Journal of Allergy and Clinical Immunology 2017 140, 145-153.e8DOI: (10.1016/j.jaci.2017.02.019) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions