Faecal carriage of extended-spectrum β-lactamase-producing Enterobacteriaceae is common 12 months after infection and is related to strain factors  E.

Slides:



Advertisements
Similar presentations
Models for the organisation of hospital infection control and prevention programmes B. Gordts Clinical Microbiology and Infection Volume 11, Pages
Advertisements

C.-S. Lee, J.-H. Lee  Clinical Microbiology and Infection 
R. Dumke, H. von Baum, P.C. Lück, E. Jacobs 
Helicobacter pylori resistance to antibiotics in 2014 in France detected by phenotypic and genotypic methods  A. Ducournau, L. Bénéjat, E. Sifré, E. Bessède,
Detection of Panton–Valentine leukocidin gene in Staphylococcus aureus by LightCycler PCR: clinical and epidemiological aspects  D. Johnsson, P. Mölling,
L. Boyanova  Clinical Microbiology and Infection 
R. Cantón, A. Novais, A. Valverde, E. Machado, L. Peixe, F. Baquero, T
The use of Raman spectroscopy in the epidemiology of methicillin-resistant Staphylococcus aureus of human- and animal-related clonal lineages  M.W.H.
S. M. Kotila, A. Virolainen, M. Snellman, S. Ibrahem, J. Jalava, O
Multiple ST clonal complexes, with a predominance of ST131, of Escherichia coli harbouring blaCTX-M-15 in a tertiary hospital in Tanzania  S.E. Mshana,
Evolution of extended-spectrum β-lactamases by mutation
L. Skjøt-Rasmussen, S. S. Olsen, L. Jakobsen, K. Ejrnæs, F. Scheutz, B
K. Diestra, E. Miró, C. Martí, D. Navarro, J. Cuquet, P. Coll, F
C.-S. Lee, J.-H. Lee  Clinical Microbiology and Infection 
Increased conjugation frequencies in clinical Enterococcus faecium strains harbouring the enterococcal surface protein gene esp  B. Lund, H. Billström,
Outcome of carbapenem resistant Klebsiella pneumoniae bloodstream infections  D. Ben-David, R. Kordevani, N. Keller, I. Tal, A. Marzel, O. Gal-Mor, Y.
Detection of Panton–Valentine leukocidin gene in Staphylococcus aureus by LightCycler PCR: clinical and epidemiological aspects  D. Johnsson, P. Mölling,
Evaluation of VITEK 2 for analysis of Enterobacteriaceae using the Advanced Expert System (AES) versus interpretive susceptibility guidelines used at.
Evidence of transmission of verocytotoxin-producing Escherichia coli O111 from a cattle stable to a child  E. Møller Nielsen, C. Jensen, D. Lau Baggesen 
P. Nordmann, L. Poirel  Clinical Microbiology and Infection 
Impact of transition from microscopy to molecular screening for detection of intestinal protozoa in Dutch patients  S. Svraka-Latifovic, S. Bouter, H.
Extended-spectrum β-lactamase/AmpC- and carbapenemase-producing Enterobacteriaceae in animals: a threat for humans?  J.-Y. Madec, M. Haenni, P. Nordmann,
Risk factors and outcome for colistin-resistant Acinetobacter nosocomialis bacteraemia in patients without previous colistin exposure  Y.-C. Wang, Y.-T.
L. Skjøt-Rasmussen, S. S. Olsen, L. Jakobsen, K. Ejrnæs, F. Scheutz, B
Klebsiella pneumoniae: development of a mixed population of carbapenem and tigecycline resistance during antimicrobial therapy in a kidney transplant.
Community-acquired methicillin-resistant Staphylococcus aureus infections: an emerging threat in Spain  A. Manzur, A.M. Dominguez, M. Pujol, M.P.M. González,
Rapid detection of enterobacteriaceae producing extended spectrum beta-lactamases directly from positive blood cultures by matrix-assisted laser desorption.
Epidemiological investigation of a case of nosocomial Legionnaires' disease in Taiwan: implications for routine environmental surveillance  S.T. Chien,
Vector control: a cornerstone in the malaria elimination campaign
B. Smith, J. T. Larsson, M. Lisby, L. Müller, S. B. Madsen, J
Training for the infectious diseases speciality in Norway
Prevalence of extended-spectrum β-lactamases in isolates of the Enterobacter cloacae complex from German hospitals  H. Hoffmann, E. Stürenburg, J. Heesemann,
Development of antimicrobial resistance in Staphylococcus lugdunensis during treatment—report of a case of bacterial arthritis, vertebral osteomyelitis.
Comparative assessment of inoculum effects on the antimicrobial activity of amoxycillin- clavulanate and piperacillin-tazobactam with extended-spectrum.
Emergence of CTX-M-15 extended-spectrum β-lactamase-producing Klebsiella pneumoniae isolates in Bosnia and Herzegovina  A. Dedeic-Ljubovic, M. Hukic,
Development and clinical validation of a molecular diagnostic assay to detect CTX-M- type β-lactamases in Enterobacteriaceae  J.D.D. Pitout, N. Hamilton,
Control of infections due to extended-spectrum β-lactamase-producing organisms in hospitals and the community  R.E. Warren, G. Harvey, R. Carr, D. Ward,
Rapid identification of uropathogenic Escherichia coli of the O25:H4-ST131 clonal lineage using the Diversi-Lab repetitive sequence-based PCR system 
Ciprofloxacin-resistant, CTX-M-15-producing Escherichia coli ST131 clone in extraintestinal infections in Italy  M. Cerquetti, M. Giufrè, A. García-Fernández,
Diarrhoeagenic microbes by real-time PCR in Rwandan children under 5 years of age with acute gastroenteritis  J.-C. Kabayiza, M.E. Andersson, S. Nilsson,
Four-year epidemiological study of extended-spectrum β-lactamase-producing Enterobacteriaceae in a French teaching hospital  L. Gibold, F. Robin, R.-N.
Metagenomics and probiotics
Neisseria meningitidis W-135 in the Basque Country, northern Spain
Klebsiella pneumoniae: development of a mixed population of carbapenem and tigecycline resistance during antimicrobial therapy in a kidney transplant.
Nationwide pseudo-outbreak of Salmonella enterica ssp
Long-term study of the frequency of Escherichia coli and Klebsiella pneumoniae isolates producing extended-spectrum β-lactamases  L. Romero, L. López,
J. Price, N. Claire Gordon, D. Crook, M. Llewelyn, J. Paul 
Persistent strains of coagulase-negative staphylococci in a neonatal intensive care unit: virulence factors and invasiveness  C. Klingenberg, A. Rønnestad,
Epidemiological investigation of a nosocomial outbreak of multidrug-resistant Corynebacterium striatum at one Belgian university hospital  A. Verroken,
Detection of nosocomial Clostridium difficile infections with toxigenic strains despite negative toxin A and B testing on stool samples  J. Stahlmann,
Effect of metronidazole versus standard care on length of stay of patients admitted with severe infectious mononucleosis: a randomized controlled trial 
Strain relatedness of meticillin-resistant Staphylococcus aureus isolates recovered from patients with repeated bacteraemia  C-H. Liao, C-C. Lai, S-Y.
Colonization of residents and staff of a long-term-care facility and adjacent acute-care hospital geriatric unit by multiresistant bacteria  A. March,
Cessation of screening for intestinal carriage of extended-spectrum β-lactamase- producing Enterobacteriaceae in a low-endemicity intensive care unit with.
Clinical and microbiological profile of persistent coagulase-negative staphylococcal bacteraemia in neonates  G. Dimitriou, S. Fouzas, N. Giormezis, I.
V. Spoorenberg, J. M. Prins, B. C. Opmeer, T. M. de Reijke, M. E. J. L
Prevalence and diversity of extended-spectrum ß-lactamases in faecal Escherichia coli isolates from healthy humans in Spain  L. Vinué, Y. Sáenz, S. Martínez,
An after-hours clinical liaison blood culture service—is it worth it?
R. Cantón, A. Novais, A. Valverde, E. Machado, L. Peixe, F. Baquero, T
Diversity of carbapenemases in clinical isolates of Enterobacteriaceae in Croatia—the results of a multicentre study  V. Zujić Atalić, B. Bedenić, E.
Methicillin-resistant Staphylococcus saprophyticus in Sweden carries various types of staphylococcal cassette chromosome mec (SCCmec)  B. Söderquist,
Results of two worldwide surveys into physician awareness and perceptions of extended-spectrum β-lactamases  H. Goossens, S. Malhotra-Kumar, H. Eraksoy,
C. Novais, T.M. Coque, J.C. Sousa, L.V. Peixe 
Predominance of SHV-5 β-lactamase in enteric bacteria causing community-acquired urinary tract infections in Bosnia and Herzegovina  S. Uzunovic-Kamberovic,
Staphylococcus lugdunensis: clinical spectrum, antibiotic susceptibility, and phenotypic and genotypic patterns of 39 isolates  C. Hellbacher, E. Törnqvist,
Genetic diversity of carbapenem-hydrolysing β-lactamases in Acinetobacter baumannii from Romanian hospitals  R.A. Bonnin, L. Poirel, M. Licker, P. Nordmann 
Typing of Clostridium difficile
Impact of antibiotic restrictions: the patient's perspective
Genetic diversity of community-associated methicillin-resistant Staphylococcus aureus in southern Stockholm,   H. Fang, G. Hedin, G. Li, C.E.
The future of diagnostic bacteriology
Presentation transcript:

Faecal carriage of extended-spectrum β-lactamase-producing Enterobacteriaceae is common 12 months after infection and is related to strain factors  E. Titelman, C.M. Hasan, A. Iversen, P. Nauclér, M. Kais, M. Kalin, C.G. Giske  Clinical Microbiology and Infection  Volume 20, Issue 8, Pages O508-O515 (August 2014) DOI: 10.1111/1469-0691.12559 Copyright © 2014 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 1 Extended spectrum β-lactamase (ESBL) -producing strains during follow up. Overview of the duration and dynamics of faecal carriage of ESBL-producing Enterobacteriaceae (EPE). (a) Results of cultures and pulsed field gel electrophoresis (PFGE) for those who were carriers at 12 months, (b) results for non-carriers. Each row shows the results for one patient. The symbols represent the species and strains where ESBL was detected in the infecting isolate and in faeces at 1, 3, 6 and 12 months. Clinical Microbiology and Infection 2014 20, O508-O515DOI: (10.1111/1469-0691.12559) Copyright © 2014 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 2 CTX-M-groups and replicon types of extended spectrum β-lactamase (ESBL) -producing strains during follow up. Overview of the patients for whom we found the ESBL production in a new species or strain during follow up. Each row shows the results of the cultures, pulsed field gel electrophoresis (PFGE), CTX-M grouping and PCR-based replicon typing for one patient. The symbols represent the species and strains where ESBL production was found as well as the CTX-M-type. The replicon types of each strain can be found next to the symbol. Clinical Microbiology and Infection 2014 20, O508-O515DOI: (10.1111/1469-0691.12559) Copyright © 2014 European Society of Clinical Infectious Diseases Terms and Conditions