Enterovirus infections in England and Wales, 2000–2011: the impact of increased molecular diagnostics S. Kadambari, A. Bukasa, I.O. Okike, R. Pebody,

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Enterovirus infections in England and Wales, 2000–2011: the impact of increased molecular diagnostics S. Kadambari, A. Bukasa, I.O. Okike, R. Pebody, D. Brown, C. Gallimore, J. Xerry, M. Sharland, S.N. Ladhani Clinical Microbiology and Infection Volume 20, Issue 12, Pages 1289-1296 (December 2014) DOI: 10.1111/1469-0691.12753 Copyright © 2014 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 1 Age distribution of laboratory-confirmed enterovirus infections in England and Wales during 2000–2011 obtained from LabBase 2. Clinical Microbiology and Infection 2014 20, 1289-1296DOI: (10.1111/1469-0691.12753) Copyright © 2014 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 2 Enterovirus seasonal trends in England and Wales during 2000–2011 obtained from LabBase 2. Clinical Microbiology and Infection 2014 20, 1289-1296DOI: (10.1111/1469-0691.12753) Copyright © 2014 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 3 Changes in the methods used for enterovirus detection in England and Wales during 2000–2011 Clinical Microbiology and Infection 2014 20, 1289-1296DOI: (10.1111/1469-0691.12753) Copyright © 2014 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 4 Enterovirus types (including untyped strains) circulating in England and Wales during 2000–2011, obtained from LabBase2. Note: enterovirus type was not reported because it was not sent to the Virus Reference Department (VRD) or because LabBase2 was not updated after results from the VRD had been reported to the local National Health Service hospital laboratory. Clinical Microbiology and Infection 2014 20, 1289-1296DOI: (10.1111/1469-0691.12753) Copyright © 2014 European Society of Clinical Infectious Diseases Terms and Conditions