Reliability of automated volumetric measurement of multiple growing follicles in controlled ovarian hyperstimulation  Frederic Lamazou, M.D., Elisangela.

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Reliability of automated volumetric measurement of multiple growing follicles in controlled ovarian hyperstimulation  Frederic Lamazou, M.D., Elisangela Arbo, M.D., Samuel Salama, M.D., Michaël Grynberg, M.D., René Frydman, M.D., Renato Fanchin, M.D., Ph.D.  Fertility and Sterility  Volume 94, Issue 6, Pages 2172-2176 (November 2010) DOI: 10.1016/j.fertnstert.2010.01.062 Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

Figure 1 The three types of measurements performed in the same selected growing follicles: (A) mean follicle diameter, (B) VOCAL volume, and (C) SonoAVC volume calculation. Fertility and Sterility 2010 94, 2172-2176DOI: (10.1016/j.fertnstert.2010.01.062) Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Box-and-whisker plot illustrating the relationship between mean follicle diameter classes and actual follicle (follicular fluid volume), VOCAL, and SonoAVC volume measurements. Horizontal lines inside the boxes represent median levels. Upper and lower limits of the boxes and whiskers represent the 75th and 25th centiles and 90th and 10th centiles, respectively. Mean follicle diameters were arbitrarily sorted into eight different groups: A, 12.0 to 12.9 mm (n = 2); B, 13.0 to 13.9 mm (n = 5); C, 14.0 to 14.9 mm (n = 13); D, 15.0 to 15.9 mm (n = 6); E, 16.0 to 16.9 mm (n = 9); F, 17.0 to 17.9 mm (n = 6); G, 18.0 to 18.9 mm (n = 9); and H, 19.0 to 19.9 mm (n = 9). Follicles measuring ≥20 mm in diameter (n = 13) were not included in the analysis. Note the poor correspondence between mean follicle diameters and follicle volumes irrespective of the assessment approach employed. Fertility and Sterility 2010 94, 2172-2176DOI: (10.1016/j.fertnstert.2010.01.062) Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

Figure 3 Reliability of VOCAL and SonoAVC volume measurements related to the actual volume (follicular fluid volume) of small and large growing follicles, represented in Bland and Altman plots. Fertility and Sterility 2010 94, 2172-2176DOI: (10.1016/j.fertnstert.2010.01.062) Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions