Comparison of the bronchoalveolar lavage fluid (BALF) levels of the three vascular endothelial growth factor (VEGF) types in healthy volunteers and patients.

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Comparison of the bronchoalveolar lavage fluid (BALF) levels of the three vascular endothelial growth factor (VEGF) types in healthy volunteers and patients with idiopathic pulmonary fibrosis (IPF) and hypersensitivity pneumonitis (HP). Comparison of the bronchoalveolar lavage fluid (BALF) levels of the three vascular endothelial growth factor (VEGF) types in healthy volunteers and patients with idiopathic pulmonary fibrosis (IPF) and hypersensitivity pneumonitis (HP). (A) There were no differences in the BALF VEGF-A levels among the three groups. (B, C) The BALF VEGF-C and VEGF-D levels were below the lower detection limits in many subjects from the three groups. The BALF VEGF-C level was significantly elevated in patients with HP compared to healthy volunteers; however, no difference was detected between patients with HP and patients with IPF. The BALF VEGF-D level was significantly elevated in patients with HP compared to patients in the other two groups. **p<0.01, *p<0.05. Masahiro Yamashita et al. BMJ Open Resp Res 2015;2:e000085 ©2015 by British Thoracic Society