Figure 1. Assembly of study cohort

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Figure 1. Assembly of study cohort Figure 1. Assembly of study cohort. aUnavailable to provide consent due to early death or discharge. ... Figure 1. Assembly of study cohort. <sup>a</sup>Unavailable to provide consent due to early death or discharge. <sup>b</sup>Died prior to neonatal intensive care unit day 3 (n = 670) or missing study maternal–neonatal and/or completion form (n = 9). Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) Clin Infect Dis, ciy1114, https://doi.org/10.1093/cid/ciy1114 The content of this slide may be subject to copyright: please see the slide notes for details.

Figure 2. A, Overall (early and hospital-associated) crude mortality rate of patient-days at risk, grouped by month of ... Figure 2. A, Overall (early and hospital-associated) crude mortality rate of patient-days at risk, grouped by month of admission to the neonatal intensive care unit (NICU) (dots). Smoothed mortality rates (line) reflect standard smoothing for exploratory data analysis. Seasonal variation was pronounced prior to the intervention compared with after the intervention. B, Crude monthly rate of suspected sepsis (dots) and smoothed monthly rate (line) of patient-days at risk, grouped by month of admission to the NICU among enrolled neonates admitted to the University Teaching Hospital NICU from September 2015 through March 2017. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) Clin Infect Dis, ciy1114, https://doi.org/10.1093/cid/ciy1114 The content of this slide may be subject to copyright: please see the slide notes for details.

Figure 3. Proportion of enrolled neonates without sepsis, with culture-negative sepsis, bloodstream infection due to ... Figure 3. Proportion of enrolled neonates without sepsis, with culture-negative sepsis, bloodstream infection due to pathogen (BSI-pathogen), and bloodstream infection due to possible contaminant (BSI-contam), stratified by intervention and birth weight. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) Clin Infect Dis, ciy1114, https://doi.org/10.1093/cid/ciy1114 The content of this slide may be subject to copyright: please see the slide notes for details.