Walid K. Abu Saleh, MD, Basel Ramlawi, MD, Oz M

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Improved Outcomes With the Evolution of a Neoadjuvant Chemotherapy Approach to Right Heart Sarcoma Walid K. Abu Saleh, MD, Basel Ramlawi, MD, Oz M. Shapira, MD, Odeaa Al Jabbari, MD, Vinod Ravi, MD, Robert Benjamin, MD, Jean- Bernard Durand, MD, Monika J. Leja, MD, Shanda H. Blackmon, MD, Brian A. Bruckner, MD, Michael J. Reardon, MD The Annals of Thoracic Surgery Volume 104, Issue 1, Pages 90-96 (July 2017) DOI: 10.1016/j.athoracsur.2016.10.054 Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Proposed management algorithm for neoadjuvant therapy of cardiac sarcomas. The Annals of Thoracic Surgery 2017 104, 90-96DOI: (10.1016/j.athoracsur.2016.10.054) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Median cumulative (Cum) survival of patients who received neoadjuvant chemotherapy (20 months) was double that of patients who did not (9.5 months, p = 0.417). Blue line indicates neoadjuvant chemotherapy; green line indicates no chemotherapy; blue hatchmarks indicate chemotherapy censored data; green hatchmarks indicate no-chemotherapy censored data. The Annals of Thoracic Surgery 2017 104, 90-96DOI: (10.1016/j.athoracsur.2016.10.054) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Patients with negative surgical margins (R0 resection) had a significantly longer median cumulative (Cum) overall survival (53.5 months) than patients who had positive margins (9.5 months, p = 0.004). Blue line indicates negative margins; green line indicates positive margins; blue hatchmarks indicate negative-margin censored data; green hatchmarks indicate positive-margin censored data. The Annals of Thoracic Surgery 2017 104, 90-96DOI: (10.1016/j.athoracsur.2016.10.054) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions