A systematic review and meta-analysis of glycemic control for the prevention of diabetic foot syndrome Rim Hasan, MD, Belal Firwana, MD, Tarig Elraiyah,

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A systematic review and meta-analysis of glycemic control for the prevention of diabetic foot syndrome Rim Hasan, MD, Belal Firwana, MD, Tarig Elraiyah, MBBS, Juan Pablo Domecq, MD, Gabriela Prutsky, MD, Mohammed Nabhan, MD, Larry J. Prokop, MLS, Peter Henke, MD, Apostolos Tsapas, MD, PhD, Victor M. Montori, MD, MSc, Mohammad Hassan Murad, MD, MPH Journal of Vascular Surgery Volume 63, Issue 2, Pages 22S-28S.e2 (February 2016) DOI: 10.1016/j.jvs.2015.10.005 Copyright © 2016 Society for Vascular Surgery Terms and Conditions

Fig 1 The process of study selection. RCTs, Randomized controlled trials. Journal of Vascular Surgery 2016 63, 22S-28S.e2DOI: (10.1016/j.jvs.2015.10.005) Copyright © 2016 Society for Vascular Surgery Terms and Conditions

Fig 2 The risk of amputation. Group A, intensive control arm. Group B, conventional control arm. CI, Confidence interval. Journal of Vascular Surgery 2016 63, 22S-28S.e2DOI: (10.1016/j.jvs.2015.10.005) Copyright © 2016 Society for Vascular Surgery Terms and Conditions

Supplementary Fig 1 (online only) The risk of neuropathic and ischemic changes. CI, Confidence interval; IV, information value. Journal of Vascular Surgery 2016 63, 22S-28S.e2DOI: (10.1016/j.jvs.2015.10.005) Copyright © 2016 Society for Vascular Surgery Terms and Conditions

Supplementary Fig 2 (online only) Neuropathy; changes in vibration threshold (fixed-effect model). CI, Confidence interval; IV, information value; SD, standard deviation. Journal of Vascular Surgery 2016 63, 22S-28S.e2DOI: (10.1016/j.jvs.2015.10.005) Copyright © 2016 Society for Vascular Surgery Terms and Conditions