An interaction between filaggrin mutations and early food sensitization improves the prediction of childhood asthma  Ingo Marenholz, PhD, Tamara Kerscher, BS, Anja Bauerfeind, PhD, Jorge Esparza-Gordillo, PhD, Renate Nickel, MD, Thomas Keil, MD, MPH, Susanne Lau, MD, Klaus Rohde, PhD, Ulrich Wahn, MD, Young-Ae Lee, MD  Journal of Allergy and Clinical Immunology  Volume 123, Issue 4, Pages 911-916 (April 2009) DOI: 10.1016/j.jaci.2009.01.051 Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Pulmonary function analysis. Mean FEV1/FVC values with SDs for children without asthma (n = 583 at age 7 years and n = 567 at age 13 years); for children with asthma, eczema, food sensitization (food), and FLG mutations (FLG mut; n = 8 and n = 6, respectively); and for all other children with asthma (n = 140 and n = 148, respectively). ∗Significantly different from the “No asthma” group. §Significantly different from the “asthma” group. Journal of Allergy and Clinical Immunology 2009 123, 911-916DOI: (10.1016/j.jaci.2009.01.051) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions