Screening and identification of tissue-specific methylation for body fluid identification Li Li Ma, Shao Hua Yi, Dai Xin Huang, Kun Mei, Rong Zhi Yang Forensic Science International: Genetics Supplement Series Volume 4, Issue 1, Pages e37-e38 (January 2013) DOI: 10.1016/j.fsigss.2013.10.018 Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions
Fig. 1 DNA methylation level at blood-specific differentially methylated regions: (a) Sequenom MassARRAY Analysis of percent DNA methylation. The EpiTYPER program provides the results of percent methylation as an epigram. The epigram shows the percent DNA methylation level of each CpG site of the target region. The aligned epigram shows methylation differences in the target genomic region. Different colours display relative methylation changes in 10% increments. The number of CpG sites, target sequence length and sample names are included in each epigram. (b) Average percent methylation level and standard deviation are indicated as bar graphs for six tDMRs. SE, semen; SA, saliva; VF, vaginal fluid; BL, blood. *Average methylation shows significant difference between blood and other body fluids (p<0.01). Forensic Science International: Genetics Supplement Series 2013 4, e37-e38DOI: (10.1016/j.fsigss.2013.10.018) Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions