Preservation of the kidney by carbon monoxide: a black swan phenomenon

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Preservation of the kidney by carbon monoxide: a black swan phenomenon Karl A. Nath  Kidney International  Volume 74, Issue 8, Pages 989-991 (October 2008) DOI: 10.1038/ki.2008.423 Copyright © 2008 International Society of Nephrology Terms and Conditions

Figure 1 Mechanisms underlying donor-kidney injury and the protective effect of carbon monoxide. The dashed arrow indicates an inhibitory effect of carbon monoxide on the degradation of cytochrome P450 heme proteins. Abbreviations: CO, carbon monoxide; ALAS-1, 5-aminolevulinic acid synthase-1; HO-1, heme oxygenase-1. Kidney International 2008 74, 989-991DOI: (10.1038/ki.2008.423) Copyright © 2008 International Society of Nephrology Terms and Conditions