Ifnlr1 is expressed in the epithelial fraction along the length of the intestine. Ifnlr1 is expressed in the epithelial fraction along the length of the intestine. (A) RNA was isolated from sites along the intestine and the lung, indicated by red boxes, whole mesenteric lymph node (MLN) and spleen, and epithelial and lamina propria (LP) fractions of the small intestine from Ifnlr1-sufficient and -deficient mice. (B) Ifnlr1 expression was quantified by quantitative real-time PCR of RNA from sites depicted in panel A. n = 4 to 6 samples per group, from two independent experiments, analyzed by Mann-Whitney test. **, P < 0.01; ns, not significant. Prox, proximal; dist, distal. Megan T. Baldridge et al. J. Virol. 2017;91:e02079-16