Volume 148, Issue 5, Pages e142-e147 (November 2015)

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Volume 148, Issue 5, Pages e142-e147 (November 2015) A 66-Year-Old Man With a Past History of Relapsing Polychondritis Presented With Right Upper Lobe Consolidation, Nodular Airway Lesions, and a Corticosteroid- Responsive Chronic Cough  Carlos D. Martínez-Balzano, MD, Andres Sosa, MD, Sean O'Reilly, MD, Yuna Gong, MD, Richard Irwin, MD, Master FCCP  CHEST  Volume 148, Issue 5, Pages e142-e147 (November 2015) DOI: 10.1378/chest.15-0498 Copyright © 2015 The American College of Chest Physicians Terms and Conditions

Figure 1 Thoracic imaging. A, Chest radiograph showing consolidation of the right upper lobe. B-D, Chest CT scan revealed right upper lobe consolidation, less extensive focal disease in the left upper lobe, and mediastinal lymphadenopathy in lung (B, C) and soft tissue (D) windows. CHEST 2015 148, e142-e147DOI: (10.1378/chest.15-0498) Copyright © 2015 The American College of Chest Physicians Terms and Conditions

Figure 2 Bronchoscopic images demonstrating nodular and plaque-like confluent lesions within the airway mucosa. A, trachea. B, Left main bronchus. CHEST 2015 148, e142-e147DOI: (10.1378/chest.15-0498) Copyright © 2015 The American College of Chest Physicians Terms and Conditions

Figure 3 Histopathologic findings from transbronchial biopsies (hematoxylin and eosin stains). A, Compressed lung parenchyma with multiple eosinophilic microabscesses (black circles) (original magnification × 4). B, A higher magnification of one of the encircled regions in A, showing an aggregate of eosinophils with bright red granules; scant fibrin (pink amorphous material) surrounding the eosinophils is shown as well (original magnification × 40). C, Bronchial wall (endobronchial lesions) with diffuse, mixed inflammatory infiltrate (original magnification × 10). D, A higher magnification of C with intravascular aggregates of eosinophils (black arrow) and scattered eosinophils and plasma cells (original magnification × 40). CHEST 2015 148, e142-e147DOI: (10.1378/chest.15-0498) Copyright © 2015 The American College of Chest Physicians Terms and Conditions

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