A. Mazón, A. Gil-Setas, L. J. Sota de la Gándara, A. Vindel, J. A

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Transmission of Streptococcus pyogenes causing successive infections in a family A. Mazón, A. Gil-Setas, L.J. Sota de la Gándara, A. Vindel, J.A. Sáez-Nieto Clinical Microbiology and Infection Volume 9, Issue 6, Pages 554-559 (June 2003) DOI: 10.1046/j.1469-0691.2003.00567.x Copyright © 2003 European Society of Clinical Infectious Diseases Terms and Conditions

Figure 1 Chronology of Streptococcus pyogenes isolates from family members during a 10-month period. A, sister 11 years; B, brother 10 years; C, brother 4 years; P, pharyngotonsillitis; ST, sore throat; PD, perianal dermatitis; SF, scarlet fever; AC, asymptomatic carrier; –, culture negative. Numbers indicate the T type. Clinical Microbiology and Infection 2003 9, 554-559DOI: (10.1046/j.1469-0691.2003.00567.x) Copyright © 2003 European Society of Clinical Infectious Diseases Terms and Conditions

Figure 2 Pulsed-field gel electrophoresis of SmaI-digested chromosomal DNA from 13 S. pyogenes isolates from family members. Lanes 1 and 15: Molecular size standard. Lanes 2–6: sibling A (isolates 393, 394, 395, 396, and 515). Lanes 7–10: sibling B (isolates 397, 398, 399, and 481). Lanes 11–14: sibling C (isolates 400, 401, 480, and 516) (Table 1). Clinical Microbiology and Infection 2003 9, 554-559DOI: (10.1046/j.1469-0691.2003.00567.x) Copyright © 2003 European Society of Clinical Infectious Diseases Terms and Conditions