Effect of Conditioning Regimen Intensity on Acute Myeloid Leukemia Outcomes after Umbilical Cord Blood Transplantation Betul Oran, John E. Wagner, Todd.

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Effect of Conditioning Regimen Intensity on Acute Myeloid Leukemia Outcomes after Umbilical Cord Blood Transplantation Betul Oran, John E. Wagner, Todd E. DeFor, Daniel J. Weisdorf, Claudio G. Brunstein Biology of Blood and Marrow Transplantation Volume 17, Issue 9, Pages 1327-1334 (September 2011) DOI: 10.1016/j.bbmt.2011.01.007 Copyright © 2011 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Leukemia-free survival of AML patients in first and second complete remission (CR1-2) who underwent umbilical cord blood hematopoietic stem cell transplantation (A) after myeloablative conditioning (MAC) (——) versus reduced-intensity conditioning (RIC) (– – –); (B) for patients receiving MAC or (C) RIC according to disease status at the time of transplantation categorized as CR1 (——), CR2 with CR1 ≥ 1 year (– – –) and CR2 with CR1 <1 year (▪▪▪▪▪). Biology of Blood and Marrow Transplantation 2011 17, 1327-1334DOI: (10.1016/j.bbmt.2011.01.007) Copyright © 2011 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 Cumulative incidence of relapse for AML patients in first and second complete remission (CR1-2) who underwent umbilical cord blood (UCB) hematopoietic stem cell transplantation (HCT) (A) after myeloablative conditioning (MAC) (——) versus reduced-intensity conditioning (RIC) (– – –); (B) for patients receiving MAC or (C) RIC according to disease status at the time of transplantation categorized as CR1 (——), CR2 with CR1 ≥1 year (– – –), and CR2 with CR1 <1 year (▪▪▪▪▪). Biology of Blood and Marrow Transplantation 2011 17, 1327-1334DOI: (10.1016/j.bbmt.2011.01.007) Copyright © 2011 American Society for Blood and Marrow Transplantation Terms and Conditions