Non-adherence to cardiovascular drugs in older patients with depression: A population- based cohort study Floor Holvast, Hans Wouters, Karin Hek, François.

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Non-adherence to cardiovascular drugs in older patients with depression: A population- based cohort study Floor Holvast, Hans Wouters, Karin Hek, François Schellevis, Richard Oude Voshaar, Liset van Dijk, Huibert Burger, Peter Verhaak International Journal of Cardiology Volume 274, Pages 366-371 (January 2019) DOI: 10.1016/j.ijcard.2018.08.100 Copyright © 2018 Terms and Conditions

Fig. 1 Flow diagram showing patient selection. All patients with a recorded episode of depression (ICPC P03/P76) in 2012 were included, and were individually matched by age and sex to patients with another psychological diagnoses (any other ICPC P-chapter diagnoses, excluding P03/P76) in 2012 and mentally healthy controls (no ICPC P-chapter diagnosis) in 2012. P03 indicates depressive symptoms, P76 indicates depressive disorder. Abbreviations: Nivel-PCD, Nivel Primary Care Database; SFK, Foundation for Pharmaceutical Statistics; ICPC, International Classification of PrimaryCare. International Journal of Cardiology 2019 274, 366-371DOI: (10.1016/j.ijcard.2018.08.100) Copyright © 2018 Terms and Conditions

Fig. 2 Survival plots of persistence by chronically used drug classes using clustered Cox regression analysis. International Journal of Cardiology 2019 274, 366-371DOI: (10.1016/j.ijcard.2018.08.100) Copyright © 2018 Terms and Conditions