Blood and Immunity Pick your line-up and create your team name! Baseball Blood and Immunity Pick your line-up and create your team name!

What is the scientific name for a white blood cell? Questions: What is the scientific name for a white blood cell? Answer: Leukocytes What happens when a blood sample is centrifuged? Answer: It separates into layers.

Questions: Plasma 55% Erythrocytes 45% This blood sample has been centrifuged identify the following: 1) name each layer and identify all components & 2) list average percentage. Plasma 55% #1 Buffy Coat = Leukocytes & Thrombocytes, less Than 1% #2 #3 Erythrocytes 45%

Identify the cells in the picture below. Questions: Answer: Erythrocytes Identify the cells in the picture below.

Identify the component of blood in the picture. Questions: Identify the component of blood in the picture. Answer: Platelets If a blood sample is centrifuged, which layers settles on top? Answer: Plasma

Which blood cell carries hemoglobin? Name the four blood types? Questions: Which blood cell carries hemoglobin? Answer: Erythrocytes Name the four blood types? Answer: A, B, AB, O

Identify the blood type. Questions: Identify the blood type. Answer: Type AB Red blood cells Plasma

Which blood cell is best described by the following? Questions: Which blood cell is best described by the following? Biconcave disk No nucleus Oxygen transporter Answer: Erythrocytes Which blood component is involved in clotting? Answer: Platelets

Which lymphocytes produce antibodies? Questions: What is an antigen? Answer: Protein located on a cell’s surface which will cause production of antibodies Which lymphocytes produce antibodies? Answer: B cells (plasma)

Identify the structure below ? Questions: What type of immunity would a vaccine provide? Natural/Artificial Active/Passive Answer: Artificially acquired active immunity Identify the structure below ? Answer: Antibody

What type of blood cells is targeted by HIV? Questions: What type of blood cells is targeted by HIV? Answer: Helper T cells Which type is known as the universal donor? Answer: Type O

Identify the two types of leukocytes. Questions: Identify the two types of leukocytes. Answer: Granulocytes & Agranulocytes What is the function of a phagocyte? Answer: engulf cells

Study the picture indicate which bracket illustrate specific immunity. Questions: Study the picture indicate which bracket illustrate specific immunity. Answer: A

Which letter indicates the antigen ? Questions: Which letter indicates the antigen ? Answer: B

Questions: Injured cells release a chemical distress signal to attract phagocytes. Answer: Chemotaxis What is the pH of blood? Answer: 7.35-7.45

What is the function of a memory cell? Questions: What is a pathogen? Answer: any disease causing agent What is the function of a memory cell? Answer: to fight future infections

Which type of T cell is responsible for signaling B cells to stop? Questions: Which type of T cell is responsible for signaling B cells to stop? What is leukemia? Answer: Overproduction of WBC Answer: Suppressor T cells

In a blood sample which occurs in the smallest amount Questions: In a blood sample which occurs in the smallest amount RBC WBC&platelets plasma ? Answer: WBC & platelets What occurs in the process known as diapedesis? Answer: WBCs squeeze between cells of blood vessel walls

What does the following allelic combination indicate, IAiO? Questions: What does the following allelic combination indicate, IAiO? Answer: heterozygous type A blood What would be the allelic combination for type AB blood? Answer: IAIB

Questions: A blood typing test show no agglutination in the anti-sera B well, but agglutination in anti-sera A or Rh wells. What is the blood type? Answer: A+ A blood typing test show agglutination in the anti-sera B well, but no agglutination in anti-sera A or Rh wells. What is the blood type? Answer: B-

Questions: Answer: Leukocyte Identify the cell in the picture below. How are platelets formed? A giant cell called a megakaryocyte (yes, you must have said this name to get the question right!) bursts and the fragments form platetlets

Questions: IA IB iO IAiO IBiO On a separate sheet of paper, construct a Punnett square illustrating the possible offspring of a type AB man and an O woman? IA IB iO IAiO IBiO

Questions: IB iO IBiO iOiO Predict the possible offspring combinations of a heterozygous B type man and an O woman? 2/4 type B or 50% 2/4 type O or 50% IB iO IBiO iOiO

Questions: IB iO IA IAIB IAiO IBiO iOiO Predict the possible offspring combinations of a heterozygous B type man and an heterozygous A type woman? 1/4 type B or 25%, 1/4 type O or 25%, 1/4 type AB or 25% , 1/4 type A or 25% IB iO IA IAIB IAiO IBiO iOiO

Antigens Present on RBC Antibodies Present in Plasma Questions: Copy down the table and complete the empty cells Blood Type Antigens Present on RBC Antibodies Present in Plasma A Anti-B B Anti-A AB Both A &B Neither Anti-A nor Anti B O A nor B Anti-A & Anti-B

Questions: Name two other functions of platelets besides clotting. When is erythropoietin released & what does it do in the body? Answer: it is released when low oxygen levels are detected by liver & kidneys… stimulates bone marrow to make more RBCs Name two other functions of platelets besides clotting. Answer: phagocytize bacteria & attract WBCs to site of inflammation

Name two functions of plasma? Questions: Name two functions of plasma? Answer: Transport nutrients & gases Helps regulate fluid & electrolyte balance Helps maintain stable pH What is hemopoiesis (or hematopoiesis) and where does it occur? Answer: blood cells formation… occurs in the bone marrow

Questions: What is the name of this process and what is occurring in each of the three stages below? Answer: Hemostasis (stoppage of bleeding)

Questions: Mark each cell with a X or a  Blood Type of Donor Blood Type of Recipient A B AB O A B AB O Unsuccessful transfusion Successful transfusion

Why is hemoglobin an important part of RBCs? Questions: Why is hemoglobin an important part of RBCs? Answer: they can carry oxygen

Questions: Use the before and after to identify the type of simulated blood Answer: AB- (anti-sera contains antibodies, wells A & B agglutinated, therefore antigen A and B must have been present in order to react with anti-sera) Before: Blood Sample only After: Blood Sample + Anti-Sera A, B and Rh