This Month in Gastroenterology

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This Month in Gastroenterology Laura Harrell, Eugene B. Chang  Gastroenterology  Volume 128, Issue 7, Pages 1765-1768 (June 2005) DOI: 10.1053/j.gastro.2005.04.017 Copyright © 2005 American Gastroenterological Association Terms and Conditions

Figure 1 PET-CT imaging of HSV1-tk transgene expression in humans. Columns 1 to 3 show the 5-mm thick coronal, sagittal, and transaxial slices respectively, from a [18F]FHBG-PET-CT study in patient 05. All sections are centered on the treated tumor lesion (dotted lines in the CT images), and show [18F]FHBG accumulation at the tumor site (arrows). Anatomometabolic correlation can be obtained by fused PET-CT imaging. The white spots on the liver seen on the CT images correspond to lipiodol (arrowheads) retention after transarterial embolization of the tumor and a transjugular intrahepatic portosystemic shunt (□). Tracer signal can be seen in the treated lesion (arrows), while no specific accumulation of the tracer can be seen in necrotic, lipiodol-retaining regions around it. H, heart; L, liver; LB, large bowel; RL, right lung; Sp, spleen. Gastroenterology 2005 128, 1765-1768DOI: (10.1053/j.gastro.2005.04.017) Copyright © 2005 American Gastroenterological Association Terms and Conditions

Figure 2 Immunocytochemistry demonstrating granular expression of pro-apoptotic molecules (A) FasL and (B,C) TRAIL in colorectal cells (original magnification, 2500×). Gastroenterology 2005 128, 1765-1768DOI: (10.1053/j.gastro.2005.04.017) Copyright © 2005 American Gastroenterological Association Terms and Conditions

Figure 3 (A) Proportion of surgical/nonsurgical patients in the infliximab and the placebo group. (B) Proportion of patients operated and time to surgery in the infliximab and the placebo group. Gastroenterology 2005 128, 1765-1768DOI: (10.1053/j.gastro.2005.04.017) Copyright © 2005 American Gastroenterological Association Terms and Conditions

Figure 4 Time-to-relapse curves according to treatment group. Gastroenterology 2005 128, 1765-1768DOI: (10.1053/j.gastro.2005.04.017) Copyright © 2005 American Gastroenterological Association Terms and Conditions

Figure 5 The distribution of Y-FISH-positive cells within the longitudinal section of a single crypt was examined in the human small intestine. Y-FISH-positive cells (green dots) dominated the crypt of a male, but no such cells were detected in the crypt of a female. The distribution of Y-FISH-positive epithelial cells (green dots) within the crypt of a female BMT recipient was patchy, both in sections with GVHD (+). Gastroenterology 2005 128, 1765-1768DOI: (10.1053/j.gastro.2005.04.017) Copyright © 2005 American Gastroenterological Association Terms and Conditions

Figure 6 Fifty percent of patients with CD have antibodies to CBir1. The level of antibody response in cohort 1 to CBir1 flagellin is shown. The gray area indicates the negative range as defined by <2 SD above the mean of the normal controls, lines indicate the median level for each group. The percentage of positive samples for each group is shown. The Wilcoxon signed-rank test was used for assessing the significance of the number of positive samples, χ2 analysis was used for the significance of OD levels of positivity. Gastroenterology 2005 128, 1765-1768DOI: (10.1053/j.gastro.2005.04.017) Copyright © 2005 American Gastroenterological Association Terms and Conditions