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Volume 9, Issue 4, Pages 331-341 (April 2008) The UK Standardisation of Breast Radiotherapy (START) Trial A of radiotherapy hypofractionation for treatment of early breast cancer: a randomised trial The Lancet Oncology Volume 9, Issue 4, Pages 331-341 (April 2008) DOI: 10.1016/S1470-2045(08)70077-9 Copyright © 2008 Elsevier Ltd Terms and Conditions

Figure 1 Trial profile for START Trial A *Only major treatment deviations listed. Minor deviations due to public holidays, machine service days, and machine breakdowns not included. The Lancet Oncology 2008 9, 331-341DOI: (10.1016/S1470-2045(08)70077-9) Copyright © 2008 Elsevier Ltd Terms and Conditions

Figure 2 Kaplan-Meier plot (A) and Nelson-Aalen cumulative hazard plot (B) of local-regional tumour relapse in 2236 patients The Lancet Oncology 2008 9, 331-341DOI: (10.1016/S1470-2045(08)70077-9) Copyright © 2008 Elsevier Ltd Terms and Conditions

Figure 3 Kaplan-Meier plot of mild/marked change in breast appearance (photographic) in 1055 patients with breast conserving surgery The Lancet Oncology 2008 9, 331-341DOI: (10.1016/S1470-2045(08)70077-9) Copyright © 2008 Elsevier Ltd Terms and Conditions

Figure 4 Forest plot of late normal tissue effects assessed as moderate/marked by patients and mild/marked from photographs The Lancet Oncology 2008 9, 331-341DOI: (10.1016/S1470-2045(08)70077-9) Copyright © 2008 Elsevier Ltd Terms and Conditions