Minimized Cardiopulmonary Bypass Reduces Retinal Microembolization: A Randomized Clinical Study Using Fluorescein Angiography Riikka Rimpiläinen, MD,

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Presentation transcript:

Minimized Cardiopulmonary Bypass Reduces Retinal Microembolization: A Randomized Clinical Study Using Fluorescein Angiography Riikka Rimpiläinen, MD, Nina Hautala, MD, PhD, Juha K. Koskenkari, MD, PhD, Jussi Rimpiläinen, MD, PhD, Pasi P. Ohtonen, MS, Pirjo Mustonen, MD, PhD, Heljä-Marja Surcel, MD, PhD, Eeva-Riitta Savolainen, MD, PhD, Martti Mosorin, MD, Tero I. Ala-Kokko, MD, PhD, Tatu Juvonen, MD, PhD The Annals of Thoracic Surgery Volume 91, Issue 1, Pages 16-22 (January 2011) DOI: 10.1016/j.athoracsur.2010.08.049 Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Retinal fluorescein angiography. (A, B) The circles indicate the sites of the microembolic signals after conventional cardiopulmonary bypass. The Annals of Thoracic Surgery 2011 91, 16-22DOI: (10.1016/j.athoracsur.2010.08.049) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Hematocrit (Hct) concentrations in the minimized cardiopulmonary bypass (MCPB) group (solid squares) and the conventional cardiopulmonary bypass (CCPB) group (open squares), with medians and interquartile ranges. Reported p values are as follows: pt indicates change over time, pg, indicates a level of difference between the groups, and pt*g indicates interaction between the groups and time. (CPB = cardiopulmonary bypass; POD = postoperative day; PREOP = preoperative.) The Annals of Thoracic Surgery 2011 91, 16-22DOI: (10.1016/j.athoracsur.2010.08.049) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Polymorphonuclear (PMN) elastase concentrations in minimized cardiopulmonary bypass (MCPB) group (solid squares) and conventional cardiopulmonary bypass (CCPB) group (open squares), with medians and interquartile ranges. Reported p values are as follows: pt indicates change over time, pg, indicates a level of difference between the groups, and pt*g indicates interaction between the groups and time. (CPB = cardiopulmonary bypass; POD = postoperative day; PREOP = preoperative.) The Annals of Thoracic Surgery 2011 91, 16-22DOI: (10.1016/j.athoracsur.2010.08.049) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions