Effect of rejuvenation hormones on spermatogenesis Jared L. Moss, M.D., Lindsey E. Crosnoe, B.S., Edward D. Kim, M.D. Fertility and Sterility Volume 99, Issue 7, Pages 1814-1820 (June 2013) DOI: 10.1016/j.fertnstert.2013.04.003 Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions
Figure 1 Rejuvenation hormones and mechanism of action. Exogenous testosterone and anabolic androgenic steroids (AAS) negatively affect the hypothalamic-pituitary-gonadal (HPG) axis. Selective estrogen receptor modulators (SERMs) block the negative feedback of estrogen on the HPG axis. Human chorionic gonadotropin (hCG) stimulates Leydig cells. Aromatase inhibitors prevent the conversion of testosterone to estrogen. Fertility and Sterility 2013 99, 1814-1820DOI: (10.1016/j.fertnstert.2013.04.003) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions