Prognostic value of cluster analysis of severe asthma phenotypes

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Presentation transcript:

Prognostic value of cluster analysis of severe asthma phenotypes Arnaud Bourdin, MD, PhD, Nicolas Molinari, PhD, Isabelle Vachier, PhD, Muriel Varrin, PhD, Grégory Marin, PhD, Anne-Sophie Gamez, MD, Fabrice Paganin, MD, PhD, Pascal Chanez, MD, PhD  Journal of Allergy and Clinical Immunology  Volume 134, Issue 5, Pages 1043-1050 (November 2014) DOI: 10.1016/j.jaci.2014.04.038 Copyright © 2014 Terms and Conditions

Fig 1 Algorithm tree of homemade cluster construction. Journal of Allergy and Clinical Immunology 2014 134, 1043-1050DOI: (10.1016/j.jaci.2014.04.038) Copyright © 2014 Terms and Conditions

Fig 2 Kaplan-Meier representation of time to first exacerbation respective to SARP clusters (P = .40). Journal of Allergy and Clinical Immunology 2014 134, 1043-1050DOI: (10.1016/j.jaci.2014.04.038) Copyright © 2014 Terms and Conditions

Fig 3 ACQ-6 score variations among SARP clusters. Categories were defined as increased (ACQ-6 score variation >0.5 points), decreased (ACQ-6 variation <−0.5), or stable (ACQ-6 variation between −0.5 and 0.5). Journal of Allergy and Clinical Immunology 2014 134, 1043-1050DOI: (10.1016/j.jaci.2014.04.038) Copyright © 2014 Terms and Conditions

Fig 4 Postbronchodilator (Post BD) FEV1 variation among SARP clusters. Journal of Allergy and Clinical Immunology 2014 134, 1043-1050DOI: (10.1016/j.jaci.2014.04.038) Copyright © 2014 Terms and Conditions

Fig 5 Kaplan-Meier representation of time to first exacerbation respective to homemade clusters (P = .99). Journal of Allergy and Clinical Immunology 2014 134, 1043-1050DOI: (10.1016/j.jaci.2014.04.038) Copyright © 2014 Terms and Conditions